Tobacco use and lower rates of higher education, markers of poor health literacy, were associated with antibiotic overprescribing for respiratory infections, as were patient age, insurance, and provider specialty. Geographic region was significant when interaction with care setting was included.

Psychotropic polypharmacy, antipsychotic, and anticonvulsant use increased with each year of follow-up. This effect was strongly mediated by the age of ADHD diagnosis with substantial increases in preschoolers but no corresponding effect in older children. It was only partially explained by physician diagnoses of concomitant mental disorders.

No abstract

The C-score was developed and validated for the identification of hospitalized patients at highest risk for pADEs. Aggregation of individual prediction models into a single score reduced its predictive power for most pADEs, compared with the individual risk models, but concentrated in the highest C-score decile a patient group more than two thirds of whom experienced at least 1 pADE.

Baseline physical function is associated with hospital readmissions. The SF-12 improves the ability to identify patients at high risk of hospital readmission.