clinical presentation, and surgical approach/outcomes, all being obtained from a prospectively managed hospital database.Results: A total of 16 patients <50 years old underwent carotid procedures. Average age was 46years (41-49), 47% were male and 75% were Caucasian. Prevalence of risk factors were on average: smoking, 94% (mean 1.3 packs per day, and 32 pack-years [range, 10-100]); hypertension, 69% (1.4 medications); diabetes, 31%; a diagnosis of hypercholesterolemia, 61% (mean total cholesterol 195 mg/dL, only one >240 mg/dL); none with creatinine >1.5 mg/dL. A total of 63% were transferred to our institution from an average distance of 142 miles. A total of 13 (81%) had neurologic events before diagnosis (69% stroke, 15% amaurosis, 8% TIA, 8% combination), the rest were asymptomatic. No carotid dissections. Duplex showed 33% had stenosis >90%, 47% had a stenosis >70%, and the rest had a stenosis 50% to 69%. Average time to surgery was 29 days (4-85; median, 15). Patch angioplasty was done in 75%, the rest with eversion. Complications included: 1 hyperperfusion syndrome, 0 new strokes or cranial nerve injuries, 1 DVT (which prolonged hospitalization). Hospitalization averaged 2.6 days (range, 1-12; mode, 1).Conclusions: Carotid endarterectomy in adults <50 most commonly follows a stroke in Caucasian patients, with a carotid stenosis >70%. Both genders are at risk, commonly have hypertension. and average >30 pack-years of smoking. Those treated do well from surgery, comparable to the outcomes published in older adults.