Patchouli (Pogostemon cablin Benth) is a plant that produces essential oils and important foreign exchange earner for Indonesia. Using superior clones  with the right fertilizer application will increase the yield of patchouli oil. The research aims to obtain patchouli plants that have the best response of urea fertilization application and optimum dosage of urea for patchouli plant growth. The study was conducted at the Politeknik Negeri lampung’s teaching farm in December 2018 until May 2019. The experiment was conducted using a factorial randomized block design (RBD), consisting of two treatment factors, namely the type of urea clone. The first factor is the type of clone consisting of 2 levels, namely NPL 9 clone and Lhokseumawe clone. The second factor is the treatment of urea doses consisting of 4 levels, namely control, 250 kg.ha-1, 300 kg.ha-1, and 350 kg.ha-1. Variables observed included plant’s height, bough, diameter, number of leaves, stalk angle, chlorophyll content, wet weight of plant, wind dry weight of plant, and yield. The results of research showed  NPL 9 clone had a superior appearance and 350 kg.ha-1 of urea dose  was the optimal dose compared to other doses and could increase patchouli yield 2,3% compared to the control treatment.