Objective: This study aims to evaluate the intervention of pharmacists for drug-related problems (DRPs) related to hemoglobin (Hb) level.Methods: This study uses a prospective pre-experimental and pre-post design. The study sample included 85 patients. All patients were interviewed, and their prescriptions were identified. Then, interventions were given to doctors and patients based on the identified DRPs. Univariate, bivariate, and multivariate data analysis with binary logistic regression analysis were used.Results: There was a significant decrease (p<0.05) in the number of DRPs before (2.85±1.82) and after (0.74±0.86) the intervention. There was also a significant increase (p<0.05) in the average Hb level before (9.29±1.39) and after (9.68±1.41) the intervention; the average increase in Hb level after the intervention was 0.39 g/dl. DRP significantly influences the changes in Hb level after the intervention. Hb level increased by 0.145 times after intervention (odds ratio=0.145, p=0.015). Conclusions:Pharmacists' intervention for DRPs can increase the success of anemia therapy of hemodialysis patients at Adjidarmo Hospital, Lebak, Banten.