Combination exercise training can improve metabolic syndrome parameters in postmenopausal women with breast cancer.

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Purpose: The purpose of this study was to examine the effects of 8 weeks moderate intensity aerobic exercise on serum retinol binding protein 4 (RBP4) levels in female athletes.Methods: Twenty female karate athletics were randomly assigned to one of the exercise group (n=10) or control group (n=10). The training group performed endurance training 3 days a week for 8 weeks at an intensity corresponding to 50-60% individual maximum oxygen consumption for 45 min.Results: Body mass and body mass index increased (P<0.05) after 8 weeks aerobic exercise compared to the control group. For waist to hip ratio (WHR), body fat percentage and maximal oxygen consumption there were no significant differences between the exercise group and the control group. There were virtually no changes in body fat percentage, fasting glucose, insulin, insulin resistance and RBP4 levels after 8 weeks training.Conclusion: Serum RBP4 level was not affected by 8-week moderate aerobic exercise in female athletes.

Treatments for breast cancer such as adjuvant chemotherapy or hormone therapy can increase bone loss. Direct toxic effects of chemotherapy agents on bone formation cells as well as breast cancer itself may cause reductions of bone mineral density (BMD) in this population. Some studies reported that aerobic and resistance exercise improves bone health in preand postmenopausal women. Therefore, the aim of this study was to investigate the effect of exercise training on BMD in postmenopausal women with breast cancer. Thirty postmenopausal women with breast cancer (58.27 ± 6.31 years) who received surgery, chemotherapy and radiotherapy and were in current hormone therapy divided into two groups: intervention and control. Subjects of intervention group performed 15 weeks exercise training including walking (2 sessions per week) and resistance training (2 sessions per week different from walking days). Subjects of control group did not participate in any physical activity or exercise training. Body weight, body mass index (BMI), VO 2 peak and lumbar spine and femur bone density was measured in two groups before and after of 15 weeks. Data analysed by using t test and covariance analysis. Results of this study indicated that after 15 weeks, there was signifi cant difference between weight, BMI and VO 2 peak in intervention and control groups (p< 0.05). Body weight and BMI decreased and VO 2 peak increased in intervention group. There was no signifi cant different between two groups in lumbar spine (F= 2.98, p= 0.096) and femur (F= 1.95, p= 0.174) BMD after 15 weeks. Body weight and BMI have protective effects on the BMD and the lower body weight and BMI, the lower BMD. Exercise training reduced body weight and BMI in subjects of this study, thus exercise training had no positive effect on BMD. Subjects in this study were in hormone therapy, and hormone therapy reduces BMD in breast cancer patients. It seems that hormone therapy has side effect on BMD in breast cancer survivor, and exercise training can not inhibit this effect. It can be concluded that the 15 weeks exercise training does no positive effect on BMD in postmenopausal women with breast cancer. on 30 April 2019 by guest. Protected by copyright.