The present work aimed to describe some important concepts regarding the reproductive physiology of pharmacological control of the estrous cycle, presenting different protocols for IATF. IATF has become one of the leading reproductive biotechnologies of economic importance in cattle production globally. The different drugs currently available on the market allow synchronization of the estrous cycle in heifers with the aim of maximizing reproductive rates. In the current literature, numerous protocols are cited capable of inducing ovulation for IATF, making it necessary to know these protocols in a broad and deep way, in order to select the best for a given situation and objective.