Background: Prostate cancer (PC) is the most frequently diagnosed cancer and a leading cause of mortality among men worldwide. There is evidence of a relationship between nativity and prostate cancer incidence; and, by 2050, one in five Americans living in the U.S. will be an immigrant. Little is known about the uptake of PSA screening for U.S.-based foreign-born men. Moreover, it is unclear if the prevalence of PSA screening changed within this population after the U.S. Preventive Services Task Force (USPSTF) 2012 recommendations against routine PSA screening. Objectives: Our objectives were to: 1) describe the factors associated with PSA screening prevalence for U.S.-based foreign-born men and 2) compare PSA screening prevalence before and after the USPSTF 2012 PSA screening recommendation for these men. Methods: Data were from the 2010 and 2015 National Health Interview Surveys and limited to men ages 40 years and older who responded to the question “Ever had a PSA test?”. Data were further limited to men who indicated that they were not born in the U.S. 50 states or the District of Columbia and were living in the U.S for five years or more. Multivariable logistic regression was used to examine determinants of PSA screening and to compare screening prevalence in 2010 and 2015. Results: The sample included 2,735 foreign-born men with the largest ethnic group being those who identify as Hispanic (46%). The final multivariable model included race/ethnicity, age, education, marital status, insurance status, survey year, and length of time living in the U.S. Asian men were less likely than non-Hispanic white men to report ever having had a PSA test (Odds Ratio (OR)=0.47, 95% Confidence Interval (CI) [0.36 – 0.61]). In addition, men who were widowed had lower odds than men who were married or living with a partner of ever having had a PSA test (OR=0.65, 95% CI [0.47 – 89]). Moreover, when compared to men who reported having a first degree relative with prostate cancer, men with unknown family history of prostate cancer had lower odds of ever having had a PSA test (OR=0.54, 95% CI [0.32 – 91]). Overall, men surveyed in 2015 were less likely to report ever having had a PSA test than those in 2010 (OR=0.76, 95% CI [0.63 – 0.92]). Conclusion: Among foreign-born men, lower odds of PSA screening prevalence was reported by men who were Asian, widowed and those with unknown family history of prostate cancer. Moreover, the USPSTF 2012 PSA recommendations against routine PSA screening appeared to lower PSA screening behaviors for these men several years later. These results can inform the development of prostate cancer interventions for this underserved group. Citation Format: Jarrett A. Johnson, Richard Moser, Gary Ellison, Damali Martin. Prostate-specific antigen (PSA) screening practices before and after the U.S. Preventive Services Task Force (USPSTF) 2012 Recommendations: A focus on foreign-born men [abstract]. In: Proceedings of the Twelfth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2019 Sep 20-23; San Francisco, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(6 Suppl_2):Abstract nr C114.

Background: Cancer control researchers studying Asian Americans face many challenges in utilizing/analyzing health survey data due to limited sample sizes and population heterogeneity resulting in underrepresented in many health surveys. National-level initiatives have begun to address this problem, including a recent White House initiative to increase representation of Asian Americans and Pacific Islanders in research, data-collection, and analysis on AAPI populations and subpopulations. Within public health and specifically behavioral epidemiology, identifying and triangulating sources of data on Asian Americans can illuminate facilitate better understanding of health outcomes as well as behavioral mediators and moderators impacting this population. Purpose of Study: This project examines federal and state health surveys relevant to cancer control to: 1) identify sources and types of Asian American data, 2) identify the gaps in behavioral research in Asian Americans and 3) facilitate research in Asian American cancer health disparities. Special attention is paid to measurement of cancer control and prevention, including relevant health behaviors and social determinants. Method: Publically available health surveys including Asian-Americans will be presented and discussed, including but not limited to: the National Health Interview Survey, National Health and Nutrition Examination Survey, Health Information National Trends Survey, the Tobacco Use Supplement to the Current Population Survey, and the California Health Interview Survey. The analysis identifies how Asian Americans are reported and classified and highlights behavioral constructs relevant to cancer incidence and mortality. Differences between surveys will be presented along with an applied example of how data from different surveys may be merged together to create larger sample sizes to increase analytic power. Discussion: The results of this project will demonstrate the utility of using multiple data sets to better understand cancer-related outcomes in Asian American populations. The applied example of a combined analysis will address analytic challenges and opportunities in studying populations with small sample sizes and with heterogeneous sub-groups using available nationally representative data. Finally, we will discuss ways in which the available data can illuminate gaps in behavioral research in cancer control among Asian Americans. Citation Information: Cancer Epidemiol Biomarkers Prev 2010;19(10 Suppl):A76.

18542 Background: Many cancer therapies can cause infertility and impaired fecundity. These are important long term outcomes of concern for survivors, which can affect their quality of life. Little is known about the socio-demographic correlates of impaired fecundity (inability to get pregnant or carry child to term) in cancer survivors. The purpose of this study is to assess socio demographic correlates of “ever pregnant” in the general American population of cancer survivors. Methods: Using data from adult (>20 years old) female cancer survivor participants of the 1999–2002 iterations of the population based cross sectional survey, National Health and Nutrition Examination Study (NHANES), we used logistic regression to examine the relationship between “ever” being pregnant and socio-demographic variables. Results: Complete data were available for 7558 females. Cancer survivors represented 8.2 % of that population. On univariate analysis, being married and having ≤ high school education were associated with a greater likelihood of “ever” pregnant compared to those unmarried and those with greater than high school education (p < .05). In cancer survivors of reproductive age (between the ages of 20 and 50) being Black or Hispanic was associated with a greater likelihood of “ever” pregnant compared to whites (p < .05). Interestingly, differences in race, income, health insurance status, and marital status were not significantly associated with “ever” pregnant on multivariate analysis of all female survivors older than 20. Conclusions: These results suggest there are differences in impaired fecundity between different groups of cancer survivors. However, questions in NHANES were not designed to explicitly examine fertility related outcomes. Additional studies that specifically examine measures of fertility in survivors are needed to understand the burden of this undesirable outcome in survivors. No significant financial relationships to disclose.

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