Purpose To address the question of whether users of herbal products (HPs) are exposed to harmful contaminants, we evaluated six HPs mostly patronized in Kumasi for heavy metal contamination and assessed the health risk associated with their use. This study is one of the first safety evaluation studies on finished multiherbal products in the region. Method Three antimalarial, two antidiabetic and one antihypertensive HPs were selected after a mini-survey and coded randomly as HP A-F. The HPs were acid digested for quantitative analysis of heavy metals using Inductively Coupled Plasma Mass Spectrometer. Hg quantification was carried out using cold vapour atomic absorption spectroscopy. Results The cancer risk estimation values for the carcinogenic metals ranged between 1.54 × 10 −9 to 3.73 × 10 −4 and were all within acceptable limits. The non-cancer health risk evaluation revealed that, some of the products pose health risk to consumers. The estimated daily intake (EDI) for As in HPF was 2.48 × 10 −4 mg/kg/day compared to the reference limit of 1.67 × 10 −4 mg/kg/ day. HPF also had high hazard index (HI) of 5.70 (HI >1) in children as compared to 1.68 (HI >1) in adults showing a 3.4 folds increase in the health risk among the former. Conclusion The six polyherbal products exhibited carcinogenic risk within acceptable limits. Although, the non-carcinogenic risk assessment of products HPA to HPE suggests safety, this can only be ascertained after further characterization of their health risks in detailed chronic toxicity studies. The high HI for product HPF suggests health risk for consumers of this product.
Introduction: Acute respiratory infections are continuously emerging. Discovered in Wuhan city, China in 2019, COV-SARS-2 and most viral respiratory diseases presently do not have a definitive cure. This paper aims to evaluate the therapeutic effectiveness of ginseng for the prevention and control of acute respiratory illness including SARS-COV-2 in the adult population. Method: We performed a systematic literature review using databases PubMed, Medline, Scopus, Google Scholar, Web of Science, and Cochrane library from 1st through the 27th of April 2020. All related articles that reported the use of Ginseng in COVID-19 patients were included in this analysis. The screening was done by 2-independent researchers. The meta-analysis was performed using a comprehensive meta-analysis package. Result: 596 articles were retrieved for the time frame. After screening, 5 articles with RCTs outcomes relevant to the review were selected. Ginseng was found to be effective in the reduction of risk by 38 % and 3-days shorter duration of acute respiratory illness (ARI) in all trials than placebo. Conclusion: As the world continues to race to find a cure, it is important to consider the use of ginseng which has been proven over the years to be effective in the treatment of acute respiratory illnesses. Further studies should however be conducted to determine the right dosage to improve efficacy and prevent adverse events.
In this study, the artificial neural network was deployed to develop a classification model for predicting the class of a drug-related suspect into either the drug peddler or non-drug peddler class. A dataset consisting of 262 observations on drug suspects and offenders in central Nigeria was used to train the model which uses parameters such as exhibit type, suspect’s age, exhibit weight, and suspect’s gender to predict the class of a suspect, with a predictive accuracy of 83%. The model sets the pace for the implementation of a full system for use at airports, seaports, police stations, and by security agents concerned with drug-related matters. The accurate classification of suspects and offenders will ensure a faster and correct reference to the sections of the drug law that correspond to a particular offence for appropriate actions such as prosecution or rehabilitation.
Purpose Drivers, travellers/tourists, pedestrians, paramedical officers, road safety officers, police officers and other security agencies in emergency times in developing countries are often challenged. The purpose of this paper is to explore the intervention of a quick mobile contact called “My Contact Person” (MCP) during such emergencies. Design/methodology/approach This study used a quantitative research method to collect data. The research tool is a researcher-made questionnaire with items developed using the five innovation dimensions and domestication. The data was analyzed with SmartPLS 3.0 software. The reliability values were above the postulated demarcation of 0.7, while the average variance extracted conforms to the norm of 0.5. The study participants were mobile phone users who own and use a mobile phone. Owing to the study’s nature, a simple random sampling technique was used to appraise 196 respondents across Nigeria’s demography. Findings The results show that the mobile users in a developing context are willing to observe “MCP’s” efficacy before they try to appropriate it to their daily lifestyle. Further, “MCP’s” compatibility with the telephone user is an antecedent of its relative advantages over the existing telephone lists. The results reveal that the respondents perceived integrating and adapting “MCP” to their daily lives as a complicated process. In this study, most participants did not regard observability and trialability as a means of appropriating MCP to their daily lifestyle. Research limitations/implications This paper’s findings’ generalizability is limited because the present study was conducted using two higher education institutions (HEI) with a relatively small sample in Nigeria. Probing MCP domestication in more institutions and other communities, as significant communities’ aside HEI use mobile phones will increase our research findings’ generalizability. A parallel investigation of a range of developed and developing countries should be explored to ascertain mobile phone users’ perceptions across context. Practical implications This study has several implications for citizens, especially in the developing world. MCP will provide quick contact opportunities to loved ones of the traumatized, saving lives by significantly avoiding worry, fear, anxiety and depression. MCP also has the potential of increasing input needs to be undertaken to accelerate the appropriate use of digital technology by health-care consumers, including enhancing education and technological literacy and providing access to low-cost digital technology. Originality/value “MCP” will be a quick intervention for drivers, travellers/tourists, pedestrians, paramedical officers, road safety officers, police officers and other security agencies in the time of emergency. For the managers, the relative advantage is the preferable factor to create awareness for “MCP”, while observability needs more effort to persuade the mobile phone users to accept and use MCP.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.