Nanofibre membranes produced through the electrospinning process have been studied extensively over the past decade for a number of high demand applications including use as tissue engineered scaffolds. Despite possessing desirable properties including high surface area to volume ratios and enhanced mechanical properties, they ultimately suffer from a lack of cellular infiltration. Variations on the process include the production of highly aligned filaments of electrospun fibres referred to as bundles and yarns. Nanofibre bundle and yarn-based scaffolds have been shown to demonstrate superior cell infiltration rates compared to traditional electrospun nonwovens while also offering the capability to be incorporated into a wider array of post-processing technologies. In this review, fibre collection techniques currently employed within the literature for the fabrication of electrospun bundles and yarns along with their applications in the field of tissue engineering will be discussed.
In the first millennium A.D. mainland Southeast Asia's first great states arise, but then in the span of a few centuries these Indianized realms collapse and their Pyu, Mon, Khmer, and Cham peoples decline. In their place Burmese, Tai, and Vietnamese states arise and go on to rule the mainland as their peoples come to dominate the second millennium. Case by case these shifts appear to be ethnic and political successions wherein the strong displace the weak, but seen together regionally the similarities suggest an agricultural change whereby an irrigated wet rice specialization from upland valleys displaced gardening and farming complexes native to the lowlands.
While Southeast Asia revolves around its cities, scholarship spins off into disciplines that ignore this fact. In a region that has known cities for two millennia, where even remote peoples have shaped themselves to or against urban rule, research goes on as if the city were an alien entity, easily factored out and best forgotten. So village studies represent these city-centred nations, and few wonder if the entrepreneurs and middle class who now explain so much might themselves be explained as urban. Our disciplines divide so deeply that no one addresses how the city organizes society and shapes the region.
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