Our objective was to characterize further the acute-phase response following endotoxin (i.e. lipopolysaccharide; LPS) exposure in the bovine. Nine pure-bred Angus castrated males (i.e. steers; average body weight ¼ 299 AE 5 kg) were used in a randomized complete block design in environmentally controlled chambers, set at thermoneutral level, to characterize the acute physiological, endocrine, immune, and acute-phase protein responses following an i.v. bolus administration of 2.5 mg of LPS/kg body weight. One day before administration of LPS, all steers were fitted with an indwelling jugular vein catheter for serial blood collection. Blood samples were collected at 30-min intervals from À2 h to 8 h relative to the LPS challenge (time 0), and serum was harvested and stored at À80 C until analyzed for concentrations of cortisol, pro-inflammatory cytokines, and acute-phase proteins. Indicators of thermal status (i.e. rectal temperature, ruminal temperature, respiration rate, sweat rate, and skin temperatures) were measured at 30-min intervals from À1 h to 6 h relative to the challenge. Endotoxin exposure increased (P50.05) serum concentrations of cortisol, tumor necrosis factor-a (TNF-a), interleukin 1-b (IL-1b), IL-6, interferon-g (IFN-g), and serum amyloid A. Respiration rate, rectal temperature, and rump skin temperature also were increased (P50.05) following LPS administration. Endotoxin exposure dramatically decreased ear skin temperature (P ¼ 0.002), but tended to increase (P50.10) ruminal temperature, shoulder skin temperature, and shoulder sweat rate. Serum concentrations of acid soluble protein, a-acid glycoprotein, IL-4 and IL-2, and rump sweat rate were not altered (P40.24) by the challenge. To our knowledge, this report is the most complete characterization of the bovine acute-phase response to a bolus-dose endotoxin challenge conducted under thermoneutral conditions and should provide foundation data for future research.

British and British x Continental steers (n = 560; initial BW = 339.4 +/- 1.76 kg) were used in a serial slaughter study with a completely random design to evaluate effects of zilpaterol hydrochloride (ZH; 8.33 mg/kg of dietary DM basis) on performance and carcass characteristics. Treatments were arranged in a 4 x 4 factorial (112 pens; 7 pens/treatment; 5 steers/pen) and included duration of ZH feeding (0, 20, 30, or 40 d before slaughter plus a 3-d ZH withdrawal period) and days on feed (DOF) before slaughter (136, 157, 177, and 198 d). No duration of ZH feeding x slaughter group interactions were detected for the performance measurements (P > 0.10). Final BW did not differ (P = 0.15) between the 0-d group and the average of the 3 ZH groups, but ADG was greater for the average of the 3 ZH groups during the period in which ZH diets were fed (P < 0.01) and for the overall feeding period (P = 0.05). As duration of ZH feeding increased, DMI decreased (P = 0.01) and G:F increased linearly (P < 0.01). With the exception of KPH (P = 0.022), no duration of ZH feeding x slaughter group interactions (P > 0.10) were detected for carcass characteristics. Regardless of the duration of ZH feeding, cattle fed ZH had greater HCW (P < 0.01), greater dressing percent (P < 0.01), less 12th-rib fat (P < 0.01), larger LM area (P < 0.01), less KPH (P = 0.03), and lower yield grade (P < 0.01) than the 0-d cattle. The 0-d group had greater marbling scores (P < 0.01) than cattle fed ZH diets, with a tendency for a linear decrease in marbling score (P = 0.10) as duration of ZH feeding was extended. A greater percentage of carcasses in the 0-d group graded USDA Choice or greater (P < 0.01) than in the 3 ZH groups, whereas the percentage of Select carcasses was greater (P = 0.01) for the 3 ZH groups. From d 0 to end (P = 0.04) and during the last 43 d on feed (P < 0.01), ADG responded quadratically to DOF before slaughter. No differences were detected among slaughter groups for DMI for the entire trial period; however, a quadratic response (P = 0.02) was observed for the final 43 d before slaughter. A quadratic response was also detected for the final 43 d before slaughter (P < 0.01) and from d 0 to end (P = 0.02) for G:F. Final BW, HCW, dressing percent, and 12th-rib fat increased linearly (P < 0.01) as DOF before slaughter increased. Our results indicate that no substantial effects on performance and carcass measurements were observed when ZH was fed for 30 or 40 d as opposed to 20 d, and that effects of ZH generally did not interact with DOF before slaughter.

A device was developed to monitor rectal temperature automatically in cattle for application in research settings. Compared with manual measurement of rectal temperature, this device decreases labor and time requirements and allows data collection without the influence of animal handling or restraint. The device consists of a custom-fabricated aluminum tail harness that supports an indwelling rectal temperature data logger. Materials cost approximately US $300 per unit, and units are completely reusable. Use of this device would increase the conditions under which accurate rectal temperature measurements can be obtained in experiments with cattle.

No abstract

Stocker cattle production practices may affect subsequent performance of cattle in economically meaningful ways. Literature was reviewed to summarize possible carryover effects of stocker cattle management on finishing performance and carcass traits. The most consistent effects of stocker phase practices on finishing-phase and carcass performance of cattle appear to be explained by changes in placement weight of feeder cattle. Increasing placement weight typically is confounded with age at placement, ADG during stocker period, and duration of the stocker period. It may also be confounded with other factors, such as season of grazing and/or finishing. Data from studies comparing calf-fed to yearling-fed cattle indicate that as age or BW at feedlot entry increased, finishing ADG, DMI, and HCW increased (P<0.01) whereas G:F and days on feed decreased (P<0.01). As age and BW at feedlot entry increased, marbling score decreased (P<0.01) whereas Warner-Bratzler shear force increased (P<0.01). Studies with yearling cattle entering the feedyard after a forage-based backgrounding phase indicate that as backgrounding ADG increased, finishing ADG, DMI, and days on feed decreased (P<0.01) yet HCW and ribeye area increased (P<0.01) with no effect (P=0.45) on marbling. Stocker cattle systems are complex, integrated systems in which producers typically seek to maximize their own economic return with little regard for subsequent performance. If cattle are owned across both stocker and finishing phases of production, then management decisions should focus on maximizing return over the entire ownership period and not just within one segment of ownership. Of the traits of feeder cattle that can be affected by stocker cattle systems, BW is the primary determinate of their value when they are placed into commercial feedyards.