Introduction: The corona virus disease 2019 (COVID-19) is a pandemic disease. Infection by COVID-19 in children is not so common but gradually the numbers of children affected with COVID-19 are increasing day by day. The epidemiological importance and clinical pattern in children with COVID-19 is now a challenge to be described by the clinicians. Objectives: To describe socio-demographic and clinical characteristics of COVID-19 infected children. Material and Methods: This cross sectional observational study was conducted among 58 COVID-19 children who were admitted in COVID-19 dedicated Kurmitola General Hospital (KGH), Dhaka from March 2020 to July 2020. Their signs, symptoms, sex, age distribution, laboratory results and familial contact were analyzed. Results: Among 58 most of the children (63.8%) were in school going age (5-15years). The number of female (39) was more than male (19) and female-male ratio was 1:0.48. Most of the children (75.9%) came from urban lower middle socioeconomic group. About 84.4% children were affected from family member. Among all, (8.6%) patients had no symptoms. Main symptoms of the children were cough (36.2%), only fever (22.4%), fever with cough (8.62%) and diarrhoea (5.2%). About 12.06% of the children had additional symptoms including sore throat, nasal congestion, fatigue, headache, body ache, vomiting, abdominal pain, convulsion and rash, 6.9% had respiratory distress and one child came with convulsion. About 12.1% patients showed lymphopenia, 18.9% showed leucopenia, 13.8% patient had neutrophillia. C-Reactive Protein (CRP) and serum ferritin were high in only 12.1% and 8.6% cases respectively. There were 29.3% patients who had normal Chest X-Ray and 58.6% had mild lesion, 8.6% had bilateral consolidation and 3.4% had patchy opacities. Conclusions: COVID-19 is not so common in children and usually presents with mild form or no sign symptoms clinically and by laboratory analysis. But it is noteworthy that they may play role in transmission of disease. JAFMC Bangladesh. Vol 16, No 2 (December) 2020: 72-75

Thromboembolic complications are well recognized events in Covid-19 infection. Most of the case fatalities are due to this event. Although any blood vessels may be involved, larger vessels are less commonly involved in this process. Here we describe a case of thrombosis of the arch of the aorta in association of Covid-19 infection in a hospitalized patient. The aim was to ensure timely identification and therapeutic intervention to prevent distal thromboembolic sequelae. Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 143-145

Background: Patients with active cancer are considered to be a high-risk group during the COVID- 19 pandemic. Reports of studies on the impact of COVID-19 infection on cancer patients in Bangladesh are sparse. This study was conducted to describe the clinical presentation and assess the outcome of COVID-19 infected cancer patients. Methods: In this prospective study, we enrolled 43 patients with active cancer from different cancer hospitals in Dhaka, Bangladesh who were tested positive for RTPCR of COVID-19. The study period was from August to October 2020 (three months) following ethical approval and informed written consent was ensured. The data were collected in a structured questionnaire form by interviewing the patients/relatives and from medical records of inpatient and outpatient departments and analyzed by SPSS version 25. Results: The mean age of the 43 study participants was 49.2 (±13.6) years with a male predominance (60.5%). The common primary malignancies were leukaemia (27.9%), carcinoma of the colon (18.6%), and carcinoma of the breast (14%). Diabetes (30.2%) and hypertension (27.9%) were the common co-morbidities. The most frequently found symptoms were fever and cough 67.4% each. Severe and critical illness were found in 27.9% and 2.3% cases respectively. 35 (81%) patients survived from COVID-19 and death was observed in 8 (19%) patients.There was no significant association of age, gender, primary malignancy type, and major co-morbidities with the outcome. Severe and critical illness were found to be significantly associated with higher mortality. Conclusions: COVID-19 related mortality is higher in cancer patients than in the general population. Mortality depends on the severity of COVID-19 in these patients, associated with severe & critical cases. Bangladesh J Medicine July 2021; 32(2) : 90-94

Background : A large number of people are becoming infected with dengue fever, which is a mosquito borne viral disease. It is mostly self-limiting, but complications can result with significant morbidity and mortality. In recent years, there has been a significant increase in the number of cases, with the majority of the population being children. There is scarcity of data regarding dengue in children in our country. Hence, to evaluate, the clinical and laboratory profile of Dengue Fever (DF) among the children and their outcome was aim of this research work. Materials and methods: This is a retrospective observational study, performed among the serologically confirmed dengue virus infected 200 children, admitted in Department of Paediatrics, Kurmitola General Hospital (KGH) Dhaka from April 2019 to December 2021. Clinical and laboratory indicators were documented daily in the study cases, and the data were analyzed by SPSS version 25. Result: Out of the 200 cases, 100 patients (50 percent) had classical DF, 61 patients (30.5 percent) had Dengue Hemorrhagic Fever (DHF) while 39 patients (19.5 percent) had Dengue Shock Syndrome(DSS). Mean age of patients were 5.8±3.6 years, male predominance. Most patients belong to urban area and middle socioeconomic background. Gastrointestinal symptoms were more prevalent in DHF patients. Most of the patients had thrombocytopenia and raised hematocrit. Thrombocytopenia, an elevated Hematocrit (hct) an elevated hypertransaminesemia were all found to be statistically significant in DHF. 85% patients were treated with crystalloid and 14% with colloid, found excellent outcome with no death. Conclusion: Dengue fever is a major health problem, with a wide range of symptoms, from mild and self-limiting to severe and fatal. Unrecognized manifestations include a wide range of symptoms spanning multiple organ systems. Doctors should be on the lookout for atypical signs and symptoms. IAHS Medical Journal Vol 4(2), December 2021; 41-45

Although Coronavirus disease (COVID-19) can affect all age groups, severity of clinical presentation among children and newborns are milder than in adults. Along with classical symptoms, atypical presentation could be noted in the neonate. We report here a case of neonatal COVID-19 where a newborn infant presented with fever, lethargy, respiratory distress and recurrent seizure. Early detection and prompt management is the prerequisite for limiting transmission and reducing neonatal death rate. Journal of National Institute of Neurosciences Bangladesh, January 2021, Vol. 7, No. 1, pp. 87-89