EGFR is expressed in most of the cases of GBC. In well-differentiated adenocarcinoma, the EGFR expression is less compared to EGFR expression in poorly differentiated tumor, leading to the conclusion that the differentiation of the tumor and EGFR expression is inversely related. Thus, intensity of EGFR expression may correlate with aggressiveness of disease.

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A case of temporal lobe hemangioma calcificans is described which is rare and less than 30 cases have been reported in the literature. This is considered to be benign variant of cerebral cavernous hemangioma. This rare case with diagnosis, treatment and clinic-pathological correlation along with review of literature is presented.