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Background Left ventricular noncompaction cardiomyopathy (LVNC) is characterized by prominent ventricular trabeculations on cardiovascular imaging. Acquired reversible LVNC has not been reported in pediatrics without a genetic background. Case presentation A 9-year-old girl with a ventriculoperitoneal (VP) shunt for neonatal posthemorrhagic hydrocephalus was referred due to exacerbation of hydrocephalus caused by VP shunt dysfunction. Transthoracic echocardiography (TTE) revealed depressed left ventricular (LV) systolic function and thick prominent trabeculae in the LV, predominantly in the apex, suggesting LVNC. Following treatment with extraventricular drainage for hydrocephalus, prominent trabeculation of the LV was diminished on TTE within 3 months. Genetic testing using next-generation sequencing was performed, and no significant variants were identified. Conclusions We revealed for the first time a pediatric case of reversible LVNC without genetic predisposition. This case report provides valuable information on the pathogenesis of acquired LVNC and suggests that detailed evaluation is required to elucidate the diagnosis of this wide spectrum of etiologic–pathogenetic disorders.

Matric suction is a crucial parameter that affects how unsaturated soils behave in terms of shear strength. Understanding it is essential for solving geotechnical problems like the stability of unsaturated soil slopes, foundations, embankments, and retaining walls. To investigate the shear behavior in unsaturated soil, a double cell triaxial test apparatus is used in the current research to carry out a series of triaxial compression tests under constant water content and constant void ratio conditions. Samples of silty soil, named DL-clay, were prepared with three different degrees of compaction: 80 %, 83 %, and 86 %, and water contents of 20 % (optimum water content) and 25 %. The soil samples were consolidated isotropically under net confining pressures of 300 kPa and 500 kPa before being sheared with constant volume. In another series of tests, water was infiltrated into the sample at 0 kPa deviatoric stress before the start of shearing with constant volume. Some specimens were also sheared with constant confining pressure for comparison purposes. From the test results, it is ascertained that maintaining a constant volume, i.e., constant void ratio during shearing, gives contour-like trajectories that can aid in defining the state boundary surface of unsaturated soil. It was also observed that within the axial strain range of 0–2 %, there was unusual behavior of a temporary sudden dip in the axial stress, which was more perceivable for samples having a high value of initial matric suction.

The presence of soil solids, water, and air complicates understanding unsaturated soil dynamics. A thorough understanding of unsaturated soil behavior is essential for the fruitful design of slopes, embankments, and retaining structures. A series of constant void ratio and constant confining pressure triaxial compression tests were carried out under constant water content conditions (pore air pressure drained and pore water pressure undrained) to study the shear strength and deformation characteristics of a partially saturated silty soil. Test specimens were prepared with a water content of 15%, 20% (Optimum water content), and 25%, with the corresponding degree of saturation of 37, 49, and 62.5%. The degree of compaction of all specimens was kept at 83% while the dry density was 1.29 g/cm3, and the void ratio was around 1.045. All the samples were isotropically consolidated under 500kPa by keeping deviatoric stress at 0kPa. The constant void ratio test results showed that the deviatoric stress reached a peak value followed by a sudden decrease within the axial strain of 0-1.5%. In contrast, the deviatoric stress increased continuously until reaching the critical state without depicting any peak for constant confining pressure tests. However, in both cases, the lower the water content at the time of specimen preparation, the higher the shear resistance.

IgA vasculitis is the most common systemic small vasculitis in children. Its major clinical manifestations are palpable purpura, arthritis and arthralgias, gastrointestinal involvement, and renal manifestations. Regarding gastrointestinal manifestations, steroids are effective in reducing abdominal pain. However, exacerbation of gastrointestinal manifestation is frequently experienced when the steroid dose is being tapered. Thus, reliable biomarkers for gastrointestinal mucosal inflammation are needed. We report the case of a 4-year-old girl with abdominal-type IgA vasculitis. During the clinical course, we used several markers, such as fecal immunochemical test, fecal α 1 -antitrypsin and calprotectin. When fecal immunochemical test showed negative results and fecal α 1 -antitrypsin value returned to the normal range, corresponding to her abdominal pain improvement, fecal calprotectin levels remained high. This suggests that fecal calprotectin is more sensitive for evaluating mucosal inflammation than other markers. It could be a useful marker for mucosal inflammation in IgA vasculitis.