Objective: To determine the association between education level and cardiometabolic risk factors in Mexican adults.Design: Case-control study. Setting and participants: Previously recollected database.Main measures: Overweight or obesity, hypertension (SAH), hyperglycemia, and hypercholesterolemia were considered as cardiometabolic risk factors. These were further associated with education levels: low, basic, middle, and superior.Analysis: Descriptive statistics, chi-square tests with subsequent odds ratio calculation for each cardiometabolic abnormality, considering the basic education level as reference (i.e., OR=1). Results:Prevalence for overweight and obesity was ≈70%, hypertension 28.1%, hypercholesterolemia 18.2%, and hyperglycemia 9.4%. SAH and hyperglycemia were inversely associated with educational level, whilst hypercholesterolemia presented the same trend up to high education but then increased when reaching a superior education level. Obesity was less prevalent in more educated subjects; but no clear-cut trend was identified for overweight. Odds ratio showed that low educational level doubles the risk of presenting all cardiometabolic abnormalities; with the exception of hypercholesterolemia. Conclusions and implications:Education level plays an important role in the presence of cardiometabolic risks, therefore it is mandatory to extend health-education policies nationwide. Background and objectiveIn Mexico, the education system scheme is divided in three broad categories: basic (preescolar, primaria (elementary), secundaria (junior high)), mid-superior (profesional técnico (technical), preparatoria (high school)), and superior (licenciatura (college), posgrado (posgraduated)) levels. Although in 2012, almost 35 million students were enrolled nationwide, completion rates (i.e., terminal efficiency) dramatically decrease as education grades increase thus, just 24 out of 100 children who started basic education level, complete the mid superior stage; and only 13 of them get the academic superior degree [1]. Finally, barely 16 of every 10,000 Mexicans undergo graduate school.Recent national surveys have reported a combined prevalence of ≈70% of adult overweight and obesity. Such abnormal nutritional statuses are major determinants for the development of diabetes mellitus (DM), systemic arterial hypertension (SAH) and cardiovascular disease. Although these cardiometabolic ailments, according to the World Health Organization (WHO), are associated to ≈30% of the worldwide deaths, the obesity-related epidemics has affected certain social groups more than others; particularly those with a lower level of education [2]. Although the association between education level and overweight/ obesity and its associated cardiometabolic consequences has been widely described [3,4], their cause-effect link is rather complex, hence the full understanding of the nature of the precise mechanisms affecting