Osteoarthritis (OA) is the most habitual type of arthritis in both developing and developed countries. It is a long-term, dynamic musculoskeletal disorder characterized by abrupt loss of cartilage in joints which results in bones rubbing together and make stiffness, impaired movement and pain. Osteoarthritis primarily affects the elderly population. It’s a significant cause of disability in elderly peoples worldwide. So the present study is done to assess the quality of life among the women with osteoarthritis, residing at Thirumazhisai. A descriptive research design was done in an urban area of Thirumazhisai. 100 women with osteoarthritis are included in our study. Purposive sampling techniques method was used in selecting the samples. Modified Knee Injury and Osteoarthritis Outcome Score(KOOS)checklist were used to collect data on quality of life among the women with osteoarthritis. The woman aged above 40 years has the percentage of mild pain (26%), moderate pain (72%), and severe pain (2%). In conclusion, women aged above 40 years were found to be experiencing moderate osteoarthritis pain and quality of life of women aged above 40 years experiencing a reasonable quality of life.