Early perinatal morbidity is increased in twin pregnancies with birthweight discordance > or =20% only when associated with fetal growth restriction and low birthweight.
Grande do Sul. Porto Alegre, RS -Brasil (F.M., J.S., R.M.)
ResumoO abuso de álcool é um dos mais sérios problemas de saúde pública e a síndrome de Wernicke-Korsakoff é uma das mais graves conseqüências do alcoolismo. Esta patologia é infreqüentemente diagnosticada nas suas apresentações menos evidentes, razão pela qual uma abordagem diagnóstica apropriada é importante passo para seu tratamento. Entre as novas propostas farmacológicas, está a reposição dos níveis de tiamina, embora isto seja insuficiente para prevenir o declínio psicológico de um grande número de pacientes. O impacto cognitivo da patologia é derivado da interação entre neurotoxicidade alcóolica, deficiência de tiamina e suscetibilidade pessoal. São descritos, a história, a epidemiologia e os achados clínicos e neuropatológicos, bem como alguns aspectos de tratamento e prognós-tico da síndrome de Wernicke-Korsakoff.
Encefalopatia de
IntrauterIne growth restrIctIon In monochorIonIc-dIamnIotIc twIns rev assoc med Bras 2014; 60(6):585-590 585Original articleIntrauterine growth restriction in monochorionic-diamniotic twins
Conflict of interest: noneObjective: to evaluate neonatal morbidity and mortality in monochorionic--diamniotic (MCDA) twin pregnancies complicated by selective intrauterine growth restriction (sIUGR) and non-selective intrauterine growth resctriction (nsIUGR). Methods: neonatal morbidity parameters and mortality were analyzed in 34 twins with IUGR (< 10 th percentile on twins' growth charts): 18 with sIUGR and 16 with nsIUGR. The sIUGR group was made up of 18 pregnancies in which growth was restricted in only one fetus (n = 18). The nsIUGR group was composed of 8 pregnancies in which both fetuses presented restricted growth (n = 16).Cases of twin-to-twin transfusion syndrome and fetal malformation were not included in the study. Results: the MCDA twin pregnancies with sIUGR had a higher rate of orotracheal intubation (p = 0.001) and mechanical ventilation (p = 0.0006), as well as longer than average fasting time (p = 0.014) compared to those in which the fetuses had nsIUGR. A higher incidence was also observed of types II and III umbilical artery Doppler velocimetry patterns in the sIUGR cases (p = 0.002). There was no significant difference between the two groups as to mortality during pregnancy and the neonatal period (p = 0.09). Conclusion: in MCDA twin pregnancies, sIUGR presents more severe umbilical artery Doppler velocimetry abnormalities and worse morbidity than nsIUGR.
OBJECTIVES:To describe the perinatal outcomes of type II and III selective fetal growth restriction (sFGR) in monochorionic-diamniotic (MCDA) twin pregnancies treated with expectant management or laser ablation of placental vessels (LAPV).METHODS:Retrospective analysis of cases of sFGR that received expectant management (type II, n=6; type III, n=22) or LAPV (type II, n=30; type III, n=9). The main outcomes were gestational age at delivery and survival rate.RESULTS:The smaller fetus presented an absent/reversed “a” wave in the ductus venosus (arAWDV) in all LAPV cases, while none of the expectant management cases presented arAWDV. The median gestational age at delivery was within the 32nd week for expectant management (type II and III) and for type II LAPV, and the 30th week for type III LAPV. The rate of at least one twin alive at hospital discharge was 83.3% and 90.9% for expectant management type II and III, respectively, and 90% and 77.8% for LAPV type II and III, respectively.CONCLUSION:LAPV in type II and III sFGR twins with arAWDV in the smaller fetus seems to yield outcomes similar to those of less severe cases that received expectant management.
Resumo: O estudo avalia a informação retida pelo paciente no Hospital São Lucas/PUC RS - Porto Alegre. Dos entrevistados, 80,80% sabem qual parte do corpo é afetada; 66,90%, o nome da doença; 48,70%, o nome do médico; 45,20%, afina/idade dos medicamentos; 34,70%, o nome desses; e 20,80%, a causa da doença. Quanto ao atendimento, os pacientes classificaram-no como ótimo (50,4%), bom (43,5%), razoável (4,3%) e ruim (17%). A única variável sócio- demográfica a influenciar o nível de informação/e o grau de instrução atribuída a uma melhor compreensão, a uma melhor informação aos pacientes de nível cultural mais elevado ou a ambas. A diferença entre grau de satisfação, alto e porcentual de informação retida baixo é discutida pelos autores. Citam-se os aspectos médico-legais da informação e são feitas recomendações na tentativa de aumentar a retenção da informação prestada, melhorando com isso a qualidade da relação médico-paciente.
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