Vestibular evoked myogenic potentials (VEMPs) in individuals with diabetes mellitus (DM) provide evidence as how diabetes can bring about changes in the peripheral nervous system. Cervical VEMP (cVEMP) evaluates the function and integrity of the sacullo- collic pathway and ocular VEMP (oVEMP) evaluates the utriculo-collic pathway. cVEMP is an ipsilateral inhibitory response of the sternocleidomastoid muscle. cVEMP is recorded at higher intensity above 80-85 dBnHL with biphasic waveforms having initial peak positivity P13 followed by a negativity N23. We performed a systematic review following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines to evaluate cVEMP in diabetes mellitus. The search was conducted in the databases: PubMed, Cumulative Index of Nursing and Allied Health Literature, Scopus, and Cochrane library using the keywords "diabetes mellitus" and "vestibular evoked myogenic potential" or "cVEMP." A two-phase selection process was used for the final inclusion of studies, and the methodological quality of these studies was assessed using the Newcastle Ottawa scale (NCOS). Meta-analysis was performed using a random-effects model. For comparisons between DM and healthy controls, a significant difference was observed for cVEMP amplitude (<i>P</i> = 0.01). Our meta-analysis's results suggest peripheral vestibular dysfunction can be observed in DM. It appears that cVEMPs may be useful in the early detection of neuropathy in DM.
Background: Coffee is a popular non-alcoholic beverage consumed by humans across the world. It contains caffeine, which is a type of stimulant of the central nervous system. In the auditory system, it has a positive effect on auditory brainstem response and perception of speech in noise. Further, caffeine has an inhibitory effect in the cochlea, but studies have rarely investigated its effect on otoacoustic emissions (OAEs) in humans. OAEs are low-intensity sounds produced by the cochlea, which could be recorded in the ear canal. The present study was carried out to investigate the effect of coffee on transient evoked otoacoustic emission (TEOAE) and contralateral suppression of TEOAE. Method: A total of 52 young adults participated in the study. A cross-over study design was used for the present investigation. The TEOAE and contralateral suppression of TEOAE were recorded before and after consumption of coffee and milk. The contralateral suppression of TEOAE was measured by presenting white noise to the contralateral ear at 40, 50, and 60 dB sound pressure level (SPL). Results: The mean amplitude of TEOAE before and after consumption of coffee was similar in both ears. Further, the mean contralateral suppression of TEOAE was slightly larger after consumption of coffee in both ears. However, the mean difference was not significant in both the ears. Conclusions: Based on the findings of present study, coffee has no significant effect on the amplitude of TEOAE and contralateral suppression of TEOAE.
Background and Objective: Binaural hearing serves as an advantage in daily communication by facilitating better localization of sounds and perception of speech in the presence of noise. BIC of ABR has been used to understand the binaural representation of different stimuli, such as transient clicks, and complex signals, such as speech. The present study aimed to investigate the test-retest reliability of the binaural interaction component for click and speech evoked ABR. Methods: 30 individuals with normal hearing served as participants for the present study. ABR for click and speech stimuli (/da/) were recorded from these participants in monaural and binaural conditions. BIC was calculated using the formula: BIC = (L + R)- BI where, L + R is the sum of the left and right evoked potentials obtained with monaural stimulation, and BI is the response acquired from binaural stimulation. To investigate reliability, all the participants underwent three recording sessions. Session 1 and session 2 (intra-session) were carried out on the same day, separately. Whereas, session 3 (inter-session) was carried out after a minimum gap of 3 - 5 days after the first session. Intraclass correlation was used to investigate the test-retest reliability of click and speech evoked BIC across the three sessions. Results: The test-retest reliability for BICclick was found to be excellent for latency measures and fair to good for amplitude measures. BICspeech was found to be fair to good, except for BIC-3. Conclusion: The results of the present study indicate that the reliability of BICclick is better than that of BICspeech. These results suggest that the clinical utility of BICspeech should be exerted with caution.
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