In calcium signalling, activation of receptor is a very significant aspect. To understand the mechanism of calcium signalling, receptors are the important components. The mobilization of intracellular calcium from intracellular stores depends upon binding of agonist to cell surface receptor. Thrombin is chosen as model ligand. In order to understand thrombin receptor activation, we analyze fractional model incorporating derivative of arbitrary order and nonsingular kernel which can precisely describe the effect of memory and can explain the model in better and more efficient manner as compared with fractional operators with singular kernels. The problem has been solved by perturbation iterative method. Using fixed-point theorem, it is proved that solution of the system will exist and also it will be unique. KEYWORDS calcium signalling, Caputo-Fabrizio fractional derivative, fixed-point theorem, fractional differential equations, thrombin MSC CLASSIFICATION Primary 26A33; Secondary 35Q92
Recently, Srivastava et al. [Integral Transforms Spec. Funct. 23 (2012), 659-683] introduced the incomplete Pochhammer symbols that led to a natural generalization and decomposition of a class of hypergeometric and other related functions as well as to certain potentially useful closed-form representations of definite and improper integrals of various special functions of applied mathematics and mathematical physics. In the present paper, our aim is to establish several formulas involving integral transforms and fractional derivatives of this family of incomplete hypergeometric functions. As corollaries and consequences, many interesting results are shown to follow from our main results.
This article aims to establish certain image formulas associated with the fractional calculus operators with Appell function in the kernel and Caputo-type fractional differential operators involving Srivastava polynomials and extended Mittag-Leffler function. The main outcomes are presented in terms of the extended Wright function. In addition, along with the noted outcomes, the implications are also highlighted.
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