Background: This study is one of very few studies which have investigated HER-2/neu expression and its correlation with histopathological finding. A total of 328 breast cancer tissue samples had been ILC are (1%), whereas positive are (1%). Lastly, HER-2/neu negative with others histological subtype are (3%), whereas positive are (0%). HER-2/neu negative histological grade I are (6%), whereas positive are (2%). HER-2/neu negative histological grade II are (21%), while positive are (7%). Lastly, HER-2/neu negative histological grade II are (40%), whereas positive are (24%). HER-2/neu negative lympho- International Journal of Medical and Health Sciences Research 2015 Vol.2, No.4, pp.62-69 ISSN(e): 2313-2752 ISSN(p): 2313-7746 DOI: 10.18488/journal.9/2015.2.4/9.4.62.69 © 2015

Autism spectrum disorder (ASD) is a collection of developmental abnormalities that can lead to significant social, communicative, and behavioral challenges. A nurse is critical in establishing a parent\'s level of autism awareness and coping skills. Our purpose was to evaluate how a parenting program for mothers influenced their ability to manage with autistic children. Quasi-interventional research, before and after the program was done. A total of 70 mothers of autistic children were enrolled in Khartoum State\'s five autism centers. The Short Form Parenting Stress Index (PSI-SF) was used to measure the level of stress and burden experienced by mothers caring for children with autism. The study showed that 31.4% of mothers had a good score in physical care skills before the intervention and 50.0% after the intervention. The mean scores of stresses pre-training 134.48 decreased to 64.1 post training program. In the pre-training program 42.90% of the mothers used problem focus coping strategy and the post-training program represented 92.85%. The educational health and counseling program played an important role in improving mothers\' ability to cope with their autistic children.

NCI-H2452 (H2452) and NCI-H28 (H28) cell lines were cultured with VER-155008 for the following analyses. The expression of HSP70 was confirmed using Western blotting. Cell viability was estimated using Cell Counting Kit-8 at 24, 48 and 72 h after adding 0.5e40 mM VER-155008 while mesothelioma cell lines were cultured on 96-well plates at 500-1000 cells/well. Colony formation and cell cycle analysis was conducted, after mesothelioma cell lines were cultured with 1e20 mM VER-155008 on 35-mm dishes. Furthermore, to estimate the synergistic effect with other anticancer drugs on cell growth, mesothelioma cell lines were cultured with VER-155008 and 0.5-5 mM cisplatin or gefitinib Result: HSP70 protein was expressed in mesothelioma cells: 211H, H2452 and H28. Its expression was not altered by VER-155008 in these cells. VER-155008 dose-dependently suppressed mesothelioma cell growth. The colony formation was significantly suppressed with VER-155008 at 20 mM. The proportion of cell counts in G1 phase significantly increased in 211H and H28 cells. Cisplatin or gefitinib did not show synergistic growth suppression after 48 h of treatment with VER-155008. Conclusion: These results suggest that VER-155008 have ability to suppress mesothelioma proliferation with G1 arrest through inhibition of HSP70 function. Furthermore, we will elucidate HSP70 function and its relationship with other mechanisms for proliferation and surviving including signal transduction and autophagy in mesothelioma.

Background: A total of 150 diabetic patients were selected retrospectively from Khartoum State Diabetic Care Centers, this group divided to two equal groups, had been analyzed using the certain complications of non-insulin dependent diabetes mellitus patients after implementation of health education program. Group (cases) the program was implemented and the other group was considered as a control (75 patients for each groupKeywords: Diabetic patients, Non-insulin-dependent, Educational health program, Diabetic complication. 2015 Vol.2, No.10, pp.171-176 ISSN(e): 2313-2752 ISSN(p): 2313-7746 DOI: 10.18488/journal.9/2015.2.10/9.10.171.176 © 2015 Contribution/ OriginalityThis study contributes in the existing literature in Khartoum State Diabetic Care Centers among Sudanese diabetic patients. This study uses new estimation methodology of implementation health education program to understand the certain complications of non-insulin dependent diabetes mellitus patients.