BackgroundThe measurement of central corneal thickness (CCT) plays an important role in the diagnosis and treatment of glaucoma and many corneal diseases.Objective of the studyTo compare the measurement of CCT by ultrasonic pachymeter with that measured by oculus pentacam in both normal subjects and patients with well-controlled glaucoma.Patients and methodsIn 173 eyes of both controls and patients with open-angle glaucoma (normal intraocular pressure) attending Ibn Al Haitham Teaching Eye Hospital, CCT was measured by oculus pentacam and then by ultrasound pachymeter at the same morning by the same technicians.ResultsThe results showed no significant difference in CCT readings measured by the two devices in both glaucoma and control groups (glaucoma group: 547.29±49.32 µm with pentacam vs 547.66±45.24 µm with ultrasound pachymeter; control group: 551.02±36.28 µm with pentacam vs 541.25±34.96 µm with ultrasound pachymeter). P-values were >0.05 in both groups (statistically not significant).Conclusion and recommendationUltrasonic pachymeter and oculus pentacam can be used interchangeably in measuring CCT, and we recommend a nontouch method (in this study, pentacam Scheimpflug camera) for measuring CCT during assessment of patients with glaucoma or any ocular disease or surgery.

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Purpose of the Study:The purpose of the study is to assess and compare the corneal flap thickness predictability and uniformity between Visumax femtosecond laser and Moria sub-Bowman keratomileusis microkeratome in laser in situ keratomileusis procedure to correct myopic and myopic astigmatism refractive errors. Methods:One hundred eyes from 100 patients, were enrolled in this study. Only one eye (right eye) of each patient was chosen for this study. They were divided into two groups of equal size (50 each). Target flap thickness was 90 μm. Flap thickness was measured by anterior segment optical coherence tomography in 7 specified positions at 3 months postoperative.Results:For femtosecond laser group, the average central flap thickness (CFT) was 91.35µm ±4.97. There was no statistically significant difference between the target flap thickness and the resultant flap thickness (p=0.12). When the central, nasal and temporal thicknesses in the same flap were compared, there was no statistically significant difference among these measurements (p=0.9).For the microkeratome group, CFT was 102.18µm±5.63. There was statistically significant difference between the target flap thickness and the resultant flap thickness (p=0.001).The central, nasal and temporal thicknesses were compared and there was a statistically significant difference.(p=0.000).Conclusions:Our study is among few studies in the literature comparing femtosecond laser flap to SBK microkeratome flap. Femtosecond laser creates more predicable flap thickness and more uniform flap architecture. It should be the first choice for the patients when the availability and cost is not a problem. TRIAL REGISTRATION: Trial registration number: NCT04684888. Trial Registration date: December 2020. Registered at www.clinicaltrials.gov.