Background (and Purpose) The aim of this study was to investigate the importance of including the measurement of bone mineral density (BMD) in reliable fracture risk assessment for women diagnosed with early nonmetastatic breast cancer (EBC) before AI treatment if zoledronic acid is not an option. Material and Methods One hundred and sixteen women with EBC were included in the study before initiating AI treatment. Most participants were osteopenic. The 10-year probability of hip fracture and major osteoporotic fracture was calculated with and without BMD based on clinical information collected at baseline using the fracture risk assessment (FRAX) tool. To compare data, the nonparametric tests were used. Results There was a significant difference (p<0.001) in the number of high-risk and low-risk FRAX score of hip fracture between before and after including BMD values. The high-risk category decreased by 50.9%, while the low-risk category increased by 42.9%. In FRAX score of major osteoporotic the findings were similar (p<0.001): The high-risk and moderate-risk category decreased by 70.4% and 4.9%, respectively, while the low-risk category increased by 43.8% when including BMD value. When stratified by age, patients aged 65 years or older were at a significantly (p<0.001) higher risk of suffering a hip or major osteoporotic fracture, highlighting the importance of including BMD measurements in this age group. Conclusions Our data support that DXA scanning of women with EBC should be performed to avoid overestimation of osteoporosis before AI treatment. It is particularly important in patients older than 65 years of age and when zoledronic acid is not an option.

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Abstract. It is well establised that inadequate physical activity can be a major risk factor for cardiovascular disease, hypertension, diabetes mellitus, prostate cancer and colon cancer. This study assessed the corrrelation of physical activity (low, moderate, high) dan screen time (acceptable, borderline excessive, excessive) in college students of the Faculty of Medicine, Unisba, academic year 2020-2021. Data was collected in a sample of 85 college student in  seven days during the Covid-19 lockdown. This research used corelation analytics with cross sectional design in the period November−December 2020. The sampling technique was done by purposive sampling. Statistical analysis using Rank Spearman test. The results showed that most (57/85 = 67%) were in the low physical activity category during their home quarantine. All students have screen time duration> 21 hours/week (excessive). The results of statistical analysis showed a weak negative correlation (value -0.155) and there was no relationship between physical activity and screen time (p = 0.156). In conclusion, there is no correlation between screen time duration and low physical activity. Abstrak. Diketahui bahwa aktivitas fisik yang kurang dapat menjadi faktor risiko utama penyakit kardiovaskular, hipertensi, diabetes melitus, kanker prostat, dan kanker usus. Penelitian ini bertujuan melihat gambaran aktivitas fisik (rendah, sedang, tinggi) dengan screen time (acceptable, borderline excessive, excessive) pada mahasiswa Fakultas Kedokteran Unisba tahun akademik 2020‒2021. Penelitian ini menggunakan analitik korelasi dengan desain cross sectional pada periode November‒Desember 2020. Teknik pengambilan sampel dilakukan secara purposive sampling. Analisis statistik menggunakan uji Rank Spearman. Hasil penelitian menunjukkan bahwa sebagian besar (57/85=67%) mahasiswa termasuk  kategori aktivitas fisik rendah selama menjalani karantina di rumah. Seluruh mahasiswa memiliki durasi screen time >21 jam/minggu (excessive). Hasil analisis statistik terdapat korelasi negatif lemah (nilai korelasi -0,155) dan tidak terdapat hubungan antara aktivitas fisik dan screen time (p=0,156). Kesimpulan, tidak terdapat hubungan lama durasi screen time dengan penurunan aktivitas fisik.