A study was conducted to assess the effect of flushing on reproduction performance (kidding type and fertility percentage) and production performance (birth weight, weaning weight of offspring and health of does). Eighty teddy does were randomly divided into two groups (n=40) viz T 1 and T 2 as control group and test group, respectively. Flushing ration 250 g and 500 g with crude protein 17.5 % and metabolizable energy 2.9 Mcal/kg was offered to does for one month prior and post breeding season (15 September-30 October). Does were weighed at the start of breeding season T 2 (BW=29.18±0.21kg) and T 1 (BW=28.93±0.53kg), respectively. All the does were sent for grazing of jantar fodder for four hours daily and were sheltered during the rest time in different pens with separate feeding during the whole experimental period. Ad libitum supply of fresh clean drinking water was made available round the clock. Exposed does were mated naturally and bucks were inducted to the exposed does for 30 minutes at morning and evening daily for teasing purpose to identify does in estrus, while separate them for breeding with enlisted buck. Mean values of Fertility rate and kidding rate in T 1 and T 2 were 75% vs 85% and 150% vs 176 % (p<0.01) showing significantly higher rate is in T 2 group. The birth weight and weaning weight of the kids in T 1 and T 2 group were 1.56±0.02 kg vs 1.87±0.04 kg and 9.0±0.21 kg vs 10.45±0.18 kg, respectively showing better results in group (T 2 ). Effect of flushing on type of birth was observed significant at Chi-square value of 9.138 p-value of 0.010 showing higher number of twin and triplet birth in test group. Furthermore, the study of growth of kids revealed a better Average daily gains in T 2 than in T 1 indicating the long term carryover effect of flushing on the body weight gains of teddy goat kids.

is an inhibitory cell surface receptor on T-cell, which is involved in the regulation of T-cell function during tolerance and immunity (Xia et al., 2018). PDCD1inhibits T-cell effector functions when binds to its ligand PDL1 and PDL2), in an antigen-specific manner. PDCD1 has been studied for cancer, human immunodeficiency virus (HIV), and Alzheimer's diseases. Overexpression of PD1

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