Aims and objectives With a focus on sexual health and rights, this study describes how transgender people experience meetings with health care professionals. Background Transgender people face prejudice and discrimination worldwide. Little is known of their experiences in sexual health‐promoting settings. Method Within a descriptive design, 20 persons aged 18–74 and identifying as transgender and nonbinary were interviewed. The results were analysed with constructivist grounded theory. Results Disrespect among health care professionals is the core category connected to the experiences in the result; transgender people experience estrangement, expectations and eviction in different sexual health‐promoting settings. Conclusion Transgender knowledge needs to be increased in general, in both specialised transgender health care and many other health care settings, to prevent transgender peoples' experiences of estrangement. Moreover, an increased knowledge of, and respect for, sexual health and rights is needed to prevent transgender peoples' exposure to gender binary, cis‐ and heteronormative expectations. In addition, access to sexual health care is essential following gender‐confirmatory care as well to avoid transgender peoples' experiences of eviction from the health care system. Relevance to clinical practice Nurses have an important role to play in striving for equity and justice within health care. This study describes how health care professionals appear to be disrespectful and suggestions of how this can be avoided are made.