People with Parkinson's disease (PD) frequently have difficulties with generating anticipatory postural adjustments (APAs) for forward propulsion and lateral weight transfer when initiating gait. This impairment has been attributed to deficits in motor planning and preparation. This study examined the preparation of APAs prior to an imperative cue to initiate forward stepping. A startling acoustic stimulus (SAS) was used to probe the state of preparation of the APA in eight PD (off medication) and seven matched control subjects. Subjects performed visually cued trials involving a pre-cue light instructing them to prepare to step, followed 3.5 s later by a go-cue light to rapidly initiate stepping. In random trials, a SAS (124 dB) was presented at -1,500, -1,000, -500, -250, -100, or 0 ms before the go-cue. Subjects also performed self-initiated steps. Ground reaction forces (GRFs), center of pressure (CoP) changes, and electromyographic (EMG) signals were recorded. The SAS triggered APAs in 94 ± 11% (PD) and 96 ± 8% (control) of trials at latencies 89 ± 4 ms (PD) and 97 ± 3 ms (control) earlier than Control trials. The temporal profile of APA preparation was similar between groups. However, peak EMG, GRF, and mediolateral CoP amplitudes were reduced in PD. SAS-evoked APAs at 0 ms matched Control trial APAs and were enhanced compared with self-initiated stepping. These results demonstrate that people with mild to moderate PD can plan and prepare the appropriate APA sequence prior to the expected cue to initiate gait; however, the prepared APAs are underscaled in magnitude.
From 1980 to 1995, annual catch rates of southern rock lobster (Jasus edwardsii) in Tasmanian waters declined from 1·6 to 0·9 kg per pot lift. From March 1998, the Tasmanian government intends to base management of this fishery on output controls using individual transferable catch quotas. This has necessitated the development of a stock assessment model that can be used to evaluate the relative merits of a variety of alternative catch limits in terms of the trade-off between protecting the rock lobster resource and achieving a high yield. Each of eight regions around Tasmania is assessed separately because of spatial heterogeneity between regions in lobster growth, size at maturity and catch rates. The stock assessment model is size-structured and is fitted to catch, effort and length–frequency data as well as to estimates of exploitation rate from experimental data. A Bayesian estimation framework is employed to estimate the quantities needed for risk analysis. Egg production differs markedly among the eight regions: from as low as 6% of the unexploited equilibrium level in the northern regions, where the growth rate is fast, to more than 80% in the south-west, where the growth rate is slowest.
In an earlier paper, outlines of footprints of persons walking normally were studied to determine whether different people make verifiably distinct footprints. Our basic null hypothesis is: given a footprint outline trace made by Subject A (Alice), then Subject B (Bob), a distinct person, cannot produce a footprint outline trace indistinguishable from that of Alice. We showed in the previous work that the probability of a chance match is less than 10−8. In this paper we report two new advances in our research. First, we establish a rigorous mathematical framework for calculating worstcase and average chance-match probabilities. Second, we repeat the previous experiment to substantiate the earlier results, but with an expanded population sample size and a more representative and significantly bigger repeated sample. These improvements and a new automated tracing procedure for extracting all numerical measures lead to a sharpened accuracy with average chance match probabilities of 7.88 × 10−10 for a general population. In other words, the odds of a chance match are one in 1.27 billion.
Comparison of the shapes of barefoot impressions from an individual with footprints or shoes linked to a crime may be useful as a means of including or excluding that individual as possibly being at the scene of a crime. The question of the distinguishability of a person’s barefoot print arises frequently. This study indicates that measurements taken from the outlines of inked footprint impressions show a great degree of variability between donors and a great degree of similarity for multiple impressions taken from the same donor. The normality of the set of measurements on footprint outlines that we have selected for this study is confirmed. A statistical justification for the use of the product rule on individual statistical precisions is developed.
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