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Mycosis fungoides is a cutaneous T-cell lymphoma of unknown etiology, thought to be a rare sequela of chronic antigenic stimulation that may occur, for example, with exposure to contact allergens. To explore this possibility, we interviewed 174 patients with mycosis fungoides and 294 randomly selected control subjects in the San Francisco, Los Angeles, and Seattle areas concerning their lifetime histories of employment, chemical exposures, allergy, atopy, and certain medical conditions. Patients reported higher prevalence of cancers other than the non-Hodgkin's lymphomas and skin cancers (relative risk = 3.3, P less than .001) and were more likely than controls to burn when exposed to the sun (for nonblacks, relative risk = 1.7, P = .01). The latter difference may reflect a manifestation rather than a precursor of the disease. We found no consistent or biologically plausible differences between patients and controls with respect to types of jobs held, or to occupational or vocational exposures to chemicals. These findings do not support the hypothesis that persistent antigenic stimulation by contact allergens is etiologically important in the pathogenesis of mycosis fungoides.

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Social work is at an important stage in its development. All professions must be responsive to changing social and economic conditions if they are to meet the needs of those they serve. This series focuses on sound practice and the specific contributions which social workers can make to the well-being of our society. The British Association of Social Workers has always been conscious of its role in setting guidelines for practice and in seeking to raise professional standards. The conception of the Practical Social Work series arose from a survey of BASW members to discover where they, the practitioners in social work, felt there was the most need for new literature. The response was overwhelming and enthusiastic, and the result is a carefully planned, coherent series of books. The emphasis is firmly on practice set in a theoretical framework. The books will inform, stimulate and promote discussion, thus adding to the further development of skills and high professional standards. All the authors are practitioners and teachers of social work representing a wide variety of experience.