The incidence of diabetes, diabetic neuro-vasculopathy and as a result, diabetic foot ulceration is a growing problem all over the world. Diabetic foot ulcers are the most common gateways to foot infection. More than 50% of ulcers will become infected at some stage. The authors review the epidemiology, risk factors, pathophysiology, diagnosis, prevention and treatment of diabetic foot infections, including osteomyelitis. Medical and surgical, local and general treatment -including the empirical and evidence-based use of antibiotics -are thoroughly reviewed.
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