Sweet's syndrome is an uncommon benign skin disorder, whose pathogenesis remains unknown. Its classic form is more common in women and presents itself as papular-nodular, painful and erythematous or violaceous lesions. It mainly affects the face, neck, and upper limbs. Fever and neutrophilic leukocytosis are also common features. Although it is considered a systemic disease marker in more than half of patients, the association of this condition with Crohn's disease is rare, with few cases reported in the literature, of which, none in Brazil. We report the case of a patient with Crohn's disease who developed the classical features of Sweet's syndrome.

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LetterLesões vesiculares e prurido intenso em paciente com sífilis secundária:manifestação clínica atípica

RESUMO -Queratodermia marginada palmar é caracterizada pela queratodermia em faixa, nos limites das partes dorsal e palmar, em disposição nas bordas cubital e radial em pacientes com intensa exposição solar. De acordo com a literatura, por si só, a queratodermia marginada palmar não é considerada uma lesão pré-maligna. Relatamos o primeiro caso de carcinoma de células escamosas ou carcinoma espinocelular sobre queratodermia marginada palmar em uma mulher de 57 anos. PALAVRAS-CHAVE -Carcinoma de Células Escamosas; Mão; Neoplasias da Pele Queratodermia Palmar e Plantar. Squamous Cell Carcinoma on Marginal Palmar Keratoderma ABSTRACT -Marginal palmar keratoderma is characterized by palmar keratoderma affecting the limits of the dorsal and palmar regions of ulnar and radial edges in patients with