No abstract

The lactone inhibits compound 48/80-induced histamine and serotonin release from mast cells in the isolated mouse jejunum.

Taking into account that the identification of novel molecules for the effective treatment of inflammatory and immune diseases is one of the main present medical needs and one of the major goals of the pharmaceutical industry, the aim of our work is intended to provide new therapeutic strategies and a deeper understanding of the mechanism of action of new drugs related to such disorders. [...]