Background: Acanthurus guttatus is distributed from the Maldives to the Hawaiian Archipelago and the Pitcairn Islands, and as north as Ryukyu Islands and as south as New Caledonia. The only known locality in the Eastern Tropical Pacific is Clipperton Atoll where three vagrant specimens have been observed. Methods: On June 2016 and April 2017 small groups of A. guttatus were observed and photographed during SCUBA diving and snorkeling surveys for touristic suitability at Isla del Coco National Park, Costa Rica. Results: Six specimens of A. guttatus were observed swimming over shallow rocky reefs at Isla del Coco, a volcanic island located in the Eastern Tropical Pacific. Conclusions: This study represents the first record of A. guttatus at Isla del Coco, the second known location of occurrence in the Eastern Tropical Pacific, and the easternmost known range for the Whitespotted surgeonfish.