Thermal lens spectrometry (1-23) continues to receive widespread attention because of the simplicity, the sensitivity, and the applicability afforded by this technique. Recently, extensive efforts have been directed toward developing the thermal lens method into a practical detector for liquid chromatography (24)(25)(26)(27)(28)(29). These approaches appear to be feasible and promising for several reasons. First, under most chromatographic conditions, the disturbances to thermal lens caused by the flow are usually tolerable (24). Secondly, the coherent laser source, when focused, provides a diffractionlimited beam size that is compatible with the small deadvolume flow cells of the high-performance liquid chromatographs (13). And thirdly, fiied-wavelength UV laser radiation replacing the conventional mercury light source is readily obtainable, for example, from a frequency-doubled Ar+ laser.This source is capable of exciting a good many molecules eluting from the column. A recent study also reveals that a laser source of relatively low power (
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.