The TMJ has been to the Dental community a key point in the search of knowledge, being it part of the temporomandibular joint complex and of the estomatognathic system which are in charge of the mastication, speech, swallowing, as well as participation in breathing and taste perception. For the majority of the women in serious state of depression, which do not respond psychotherapeutic treatment, pharmacological treatment it's applied. The antidepressants serotonin selective reuptake inhibitors (SSRIs) are the most recommended in these cases. The teratogenic effect of the SSRIs is considered controversial, studies done with women who used these drugs during the pregnancy showed that the respiratory and central nervous systems are the most affected, was also recorded a deficit of body growth and the decrease of the encephalon and skull measures. In the present study, our goal was to assess whether the administration of Fluoxetine during the pregnancy modified the embryology and morphology of the TMJ of rats. For that, 16 Wistar female rats from the Nutrition Department of the UFPE vivarium were selected; 8 for the control group, which received daily 0.9% of saline in subcutaneous dose of 10ml/g, with schedules previously established after daily weighing and 8 for the experimental one that were treated with fluoxetine hydrochloride with the dose of 10mg/Kg in a volume 10ml/g of weight, were injected subcutaneously with the same standards established for the control group. It was observed, with this dose that the embryological development of the TMJ, especially of the mandibular condyle, does not present any difference between the degree of maturation of the tissue that forms the TMJ, especially of the condyle between the treated and control groups.

Ratos wistar; Carcinoma in situ; Carcinoma de células escamosas. Wistar rats; Carcinoma in situ; Squamous cell carcinoma. Objecti ve: To induce carcinogenesis on the lingual mucosa of Wistar rats by the administrati on of nitroquinoline oxide (4NQO), relati ng the clinical and microscopic alterati ons developed during the ti me of exposure to the carcinogenic agent. Methods: Twenty rats were allocated to either an experimental (15 animals) or a control (5 animals) group. In the experimental group, the animals were divided into 3 subgroups in which 5 animals received 4NQO during 2 months (A1), 5 during 3 months (A2), and 5 during 4 months (A3), making it possible to detect the diff erent phases of carcinogenesis. Data were presented as descripti ve stati sti cs using the Kruskal-Wallis and Mann-Whitney tests in the SPSS (Stati sti cal Package for the Social Sciences) soft ware, version 13.0. The signifi cance level was set at 5.0%. Results: Both the animal model and the carcinogenic agent used in the study were sati sfactory for inducing similar oral carcinogenesis to the one occurring in humans. The clinical alterati ons were more accentuated in the animals that received the topical applicati ons of 4NQO during 4 months, ranging from leukoplakia to erythroleukoplakias regions. The histopathological alterati ons observed in the oral epithelium were compati ble with the diagnosis of mild, moderate and severe epithelial dysplasia, in situ carcinoma or invasive carcinoma. Conclusion: The severity of the lesions had a direct relati onship with the exposure ti me to 4NQO.

Objective: to analyze the methodology of Central Venous Pressure measurement in Intensive Care Units of public hospitals in the city of Recife-PE identifying the External Reference Point. Method: this is a study of observation with the participation of 36 health professionals from nine public hospitals. The data was collected with a device validated by experts, after approved by the Ethics and Research Committee of Agamenon Magalhães Hospital, under protocol N° 54, CAAE-1219.0.000.236-10.  Results: 41% declared that they had not received training; 39% did not perform hand washing and 75% did not use a level indicator to confirm the phlebostatic axis. There was no identification for the solution in use (94%) or the equipment (67%). The prevalent External Reference Point was the External Line, but there was not a standard among these hospitals. Performing this analysis descriptively, it was noticed that the nurses had a better performance compared to the average of the nursing assistants, as well as between hospital staff that presented manual of standards and routines compared to those in institutions that had not been working with the manual. Conclusion: taking into consideration the public institutions surveyed, the measurement was not performed properly, there was not a standardization of this procedure and many professionals reported the lack of training. There was even a gap between the training and the retraining of nursing staff. Descriptors: central venous pressure, nursing, continuing education, nursing practice guideline, intensive care units.RESUMOObjetivo: analisar a metodologia da aferição da Pressão Venosa Central em Unidades de Terapia Intensiva de hospitais públicos da cidade de Recife/PE identificando o Ponto Externo de Referência. Método: trata-se de um estudo observacional no qual participaram 36 profissionais de saúde de nove hospitais públicos. Os dados foram coletados com instrumento validado por especialistas, após aprovação pelo Comitê de Ética e Pesquisa do Hospital Agamenon Magalhães, sob protocolo n.º 54, CAAE-1219.0.000.236-10. Resultados: 41% afirmaram que não tinham recebido treinamento; 39% não realizavam lavagem das mãos e 75% não utilizavam uma régua de nível para confirmar o eixo flebostático. Não existia identificação na solução utilizada (94%) e no equipo (67%). O Ponto Externo de Referência predominante era a Linha External, mas não existia uma homogeneidade entre alguns dos hospitais. Por análise descritiva, o desempenho dos enfermeiros, comparado com a média ponderada dos técnicos, foi melhor, assim como entre profissionais de hospitais que apresentaram manual de normas e rotinas, comparados aos de instituições que não tinham utilizado esse manual. Conclusão: nas instituições públicas pesquisadas a aferição não era realizada de maneira adequada, não existia uma padronização do procedimento e muitos profissionais relataram não haver treinamento. Existia ainda uma lacuna entre o treinamento e a reciclagem dos profissionais da equipe de enfermagem. Descritores: pressão venosa central, enfermagem, educação continuada, guia de prática em enfermagem, unidades de terapia intensiva.RESUMEN Objetivo: analizar la metodología de la medición de la Presión Venosa Central en Unidades de Terapia Intensiva de hospitales públicos de la ciudad de Recife – PE identificando el Punto Externo de Referencia. Método: se trata de un estudio observacional en el cual participaron 36 profesionales de la salud de nueve hospitales públicos. Los datos fueron recolectados a través de un instrumento validado por especialistas, después de ser aprobado por el Comité de Ética e Investigación del Hospital Agamenon Magalhães, con el protocolo n. 54, CAAE-1219.0.000.236-10. Resultados: el 41% afirmó no haber recibido entrenamiento; el 39% no realizaba lavajes de manos y el 75% no utilizaba una regla de nivel para confirmar el eje flebostático. No había identificación en la solución utilizada (94%) y en el equipo (67%). El Punto Externo de Referencia predominante era la Línea Esternal, pero no había una homogeneidad entre algunos de los hospitales. Por análisis descriptivo, el desempeño de los enfermeros, comparado con el promedio ponderado de los técnicos, fue mejor, así como entre profesionales de hospitales que habían presentado manual de normas y rutinas, comparados con los de instituciones que no habían usado ese manual. Conclusión: en las instituciones públicas investigadas la medición no era realizada de manera adecuada, no había una uniformidad de procedimiento y muchos profesionales relataron que no había entrenamiento. Aún así, existe una laguna  entre el entrenamiento y el reciclaje de los profesionales del equipo de enfermería. Descriptores: presión venosa central, enfermería, educación permanente, guía de práctica en enfermería, unidades de terapia intensiva.

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