Two new pentacyclic triterpenes 8,26-cyclo-urs-21-en-3β, 20β-diol (1) and 3β-acetoxy-8.26- cyclo-ursan-20β-ol (2) together with 3-friedelanone, oleanolic acid, betulinic acid, lupeol acetate, α- and β-amyrine, S.SJ^'-tetrahydroxyflavane, and 3,5,7,3',4'-pentahydroxyflavane were isolated from the stem bark of Ficus cordata (Moraceae). The structures of these secondary metabolites were established using ID and 2D NMR spectra and by comparison with published data or with authentic samples. Compounds 1 and 2 exhibited weak antibacterial and no antifungal activity.

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A new triterpene, conrauidienol (1), and a new dihydroflavonol, conrauiflavonol (2), along with bamyrin acetate (3), betulinic acid (4), ursolic acid (5), 6b-hydroxystigmasta-4,22-dien-3-one (6), 8-prenylapigenin (7), b-sitosterol glucoside (8), and 3,4',5-trihydroxy-6'',6''-dimethylpyrano[2,3-g]flavone (9) were isolated from the stem barks of Ficus conraui Warburg (Moraceae). Their structures were elucidated by spectroscopic analysis. The hexane, AcOEt, and MeOH extracts, as well as the new isolated compounds exhibited selective antimicrobial activities varying from weak to moderate.

Terpenes U 0200 Pentacyclic Triterpenes and Other Constituents from Ficus cordata (Moraceae). -The new terpenes (I) and (II) only exhibit weak antibacterial activity and no antifungal activity. -(POUMALE*, H. M. P.; KENGAP, R. T.; TCHOUANKEU, J. C.; KEUMEDJIO, F.; LAATSCH, H.; NGADJUI, B. T.