The objective was to evaluate the effect of oral administration of Lactobacillus plantarum CAM6 strain as an alternative to antibiotics in weaned pigs on productive parameters, blood biochemical profile, and IgA serum levels. Thirty-six 21-day-old weaned piglets were randomly assigned to three groups with three replicates of four piglets each. Treatments consisted of a basal diet (BD; T0) without probiotics or antibiotics; BD + antibiotics and the same basal diet used in T0 plus oral administration of 5 mL × 109 CFU/mL of L. plantarum CAM-6 (T2). During the study (21 to 49 days of age) T2 obtained a similar live weight, weight gain, and feed conversion ratio when compared to the T1. Both treatments were better in these variables compared to T0 (p ≤ 0.05). Furthermore, T2 increased serum IgA levels (p ≤ 0.05). Additionally, hematological parameters and acid-base balance remained similar in all groups. However, significant reductions in the mean corpuscular hemoglobin concentration, platelets, and metabolic hydrogen ions were observed in T1 (p ≤ 0.05). The results of this study suggest that supplementation with L. plantarum CAM6 can be an alternative to antibiotics. Studies to evaluate its efficacy under commercial conditions and water administration require further evaluation.

Background. To evaluate the biological response of the sows and their offspring with oral administration of Lactobacillus plantarum CAM6 in breeding sows, a total of 20 Pietrain breeding sows with three farrowings and their descendants were used, randomly divided into two groups of 10 sows each. Treatments included a basal diet (T0) and basal diet +10 mL biological agent containing 109 CFU/mL L. plantarum CAM6 (T1). No antibiotics were used throughout the entire experimental process of this study. Results. The L. Plantarum CAM6 supplementation in sows’ feeding did not affect ( P > 0.05 ) the reproductive performance of the sows; however, the number of deaths for their offspring before weaning ( P ≤ 0.05 ) decreased. In addition, the oral administration of Lactobacillus plantarum CAM6 in sows increased ( P ≤ 0.05 ) the content of lactose, nonfat solids, mineral salts, and the density of sows’ milk, with a decrease in milk fat. Moreover, the probiotic feed orally to the sows improved the body weight ( P ≤ 0.05 ) and reduced the diarrhea incidence of their offspring ( P ≤ 0.05 ). Also, the probiotic administration of sows changed ( P ≤ 0.05 ) the serum concentration of Na+, pCO2, and D-β-hydroxybutyrate and increased ( P ≤ 0.05 ) the leukocytes, lymphocytes, and platelets in their piglets. Conclusion. Oral administration of Lactobacillus plantarum CAM6 in breeding sows improved body weight, physiological status, and the health of their offspring. And preparing the neonatal piglets physiologically is of great importance to the pig farming industry which could decrease the operational cost and medication (especially antibiotics) consumption of the pig producers.

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ResumenObjetivo: Conocer los patrones de compromiso cardíaco en pacientes infectados por el virus de inmunodeficiencia humana en estadio SIDA. Material y Métodos: Estudio prospectivo de pacientes ambulatorios del Hospital Nacional Guillermo Almenara Irigoyen (HNGAI), que incluyó una evaluación de los parámetros clínico-epidemiológicos, así como una evaluación ecocardiográfica realizada entre marzo de 2002 y marzo de 2003. Resultados: Ciento treinta y dos pacientes fueron evaluados. Tuvieron 40,4 años en promedio (DE 8,7). La mediana del tiempo de diagnóstico fue 48 meses (RIQ 50) y recibieron terapia antiretroviral 63,6%. Los patrones de compromiso cardíaco fueron agrupados en disfunción diastólica (DD) en 28,8%, disfunción sistólica en 3,0%, y derrame pericárdico en 9,1%. La DD se asoció a una historia de internamientos anteriores así como a una mayor edad. Conclusiones: Encontramos un alto porcentaje de anormalidades cardíacas en pacientes ambulatorios con SIDA. La DD fue el hallazgo más frecuente. Palabras clave: Síndrome de inmunodeficiencia adquirida; enfermedades cardiovasculares; ecocardiografía. Cardiac compromise in AIDS. First peruvian report AbstractObjective: To determine the patterns of cardiac compromise in patients infected by human immunodeficiency virus in AIDS-stage. Material and Methods: Prospective study of ambulatory patients at Guillermo Almenara Irigoyen National Hospital between March 2002 and March 200, included assessment of clinical and epidemiological parameters and echocardiographic study. Results: One hundred and thirty-two patients were studied. They had a mean age of 40,4 years (SD 8,7). The median time for AIDS diagnosis was 48 months (IQR 50) and received antiretroviral therapy 63,6%. Cardiac compromise patterns were diastolic dysfunction (DD) in 28,8%, systolic dysfunction in 3,0%, pericardial effusion in 9,1%. DD was associated with a history of previous hospitalization and older age. Conclusions: We found a high percentage of cardiac abnormalities in patients with HIV infection in AIDS stage. DD was the most frequent finding.

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