Resolving the order of events that occurred during the transition from prokaryotic to eukaryotic cells remains one of the greatest problems in cell evolution. One view, the Archezoa hypothesis, proposes that the endosymbiotic origin of mitochondria occurred relatively late in eukaryotic evolution and that several mitochondrion-lacking protist groups diverged before the establishment of the organelle. Phylogenies based on small subunit ribosomal RNA and several protein-coding genes supported this proposal, placing amitochondriate protists such as diplomonads, parabasalids, and Microsporidia as the earliest diverging eukaryotic lineages. However, trees of other molecules, such as tubulins, heat shock protein 70, TATA box-binding protein, and the largest subunit of RNA polymerase II, indicate that Microsporidia are not deeply branching eukaryotes but instead are close relatives of the Fungi. Furthermore, recent discoveries of mitochondrion-derived genes in the nuclear genomes of entamoebae, Microsporidia, parabasalids, and diplomonads suggest that these organisms likely descend from mitochondrion-bearing ancestors. Although several protist lineages formally remain as candidates for Archezoa, most evidence suggests that the mitochondrial endosymbiosis took place prior to the divergence of all extant eukaryotes. In addition, discoveries of proteobacterial-like nuclear genes coding for cytoplasmic proteins indicate that the mitochondrial symbiont may have contributed more to the eukaryotic lineage than previously thought. As genome sequence data from parabasalids and diplomonads accumulate, it is becoming clear that the last common ancestor of these protist taxa and other extant eukaryotic groups already possessed many of the complex features found in most eukaryotes but lacking in prokaryotes. However, our confidence in the deeply branching position of diplomonads and parabasalids among eukaryotes is weakened by conflicting phylogenies and potential sources of artifact. Our current picture of early eukaryotic evolution is in a state of flux.
Micro familial non-medullary thyroid cancers are more common than previously reported and further studies are required to be able to distinguish this subgroup from sporadic papillary microcarcinomas. The careful pathological review of the familial non-medullary thyroid cancer in this study does not seem to point to a distinct subgroup of familial differentiated thyroid carcinoma although the data are intriguing. Genetic studies are now required to investigate this issue.
INTRODUCTIONNutrition plays a quintessential role with regard to maternal and child health. However, this aspect is inevitably interlinked to perceived notions and beliefs with regard to food to be consumed by pregnant and lactating women. Studies have also shown existence of practices and beliefs like denying pregnant and lactating women of known nutritious food items owing to their traditional food habits. [1][2][3] In India most food practices and traditions have stemmed from deeply rooted traditions and customs. These food practices can be attributed to malnutrition, which in turn is linked to poverty, food insecurity, unhygienic practices and traditional beliefs. 4 Beliefs are crucial in the acceptance, rejection and promotion of certain food items. These beliefs are the products of social interactions and faith which are entrenched in the minds of the community. Many of these food practices arise from the ignorance about the nutritive value of food. Most often certain cultural beliefs and practices concerning food items are due to ignorance. ABSTRACTBackground: Poor maternal nutrition adversely affects pregnancy and birth outcomes, particularly vulnerable are the rural women in a rural setting. A lactating mother"s nutritional requirement should meet needs of self and that of an infant. In most rural communities this situation is further complicated by food taboos, consequently either adding to or leading to additional negative balance of nutrients. Aims: To assess the food practices and beliefs during pregnancy and lactation among women residing in a rural area of Bangalore urban district. Methods: Study was conducted during the period of January to March 2014 among the women residing under the Sarjapur PHC, Bangalore. Data was collected using Focus Group Discussions (FGDs) and in Depth Interviews (IDIs). Thematic frame work approach was used for data analysis. Results: A total of four FGDs and twelve IDIs were conducted. Good practices included consuming green leafy vegetables, rice, bread, jowar, meat, egg and fruits like apple and mosambi. The practices which may potentially harm the health included avoidance of food items like ragi, papaya, mango and guava during pregnancy and reduced water consumption during the post natal period. Beliefs like "casting an evil eye" or "colour of the baby" had an influence on the food given to antenatal mother. Conclusions: The study found numerous food items which are nutritious and safe and available locally either restricted or denied thus making women (pregnant and lactating) and infants vulnerable. There is need for health education programs in rural areas regarding nutrition which will in turn improve the maternal and child health.
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