Spinal drug delivery is a generally safe and effective therapy for the treatment of both acute and chronic pain. However, it can be occasionally associated with significant complications, including neurologic injury, as a result of bleeding and infection in a confined space. This article focuses on risk factors for developing epidural catheter-related infections as well as strategies to minimize risks. Additionally, the diagnosis and management of epidural catheter-related infections, both superficial and deep, are discussed.

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