No abstract

To investigate skin manifestations of the polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome and their correlation with serum vascular endothelial growth factor (s-VEGF-A) levels and to describe the impact of autologous peripheral blood stem cell transplantation (aPBSCT) on these manifestations and the correlation with s-VEGF-A levels.

Highlights d Integrative analysis of ENBs identifies neural-like and basallike subgroups d Approximately 35% of basal-like ENBs display IDH2 R172 hotspot mutations d ENBs with IDH2 mutations display a CpG island methylator phenotype (E-CIMP) d Basal-like ENBs display higher intratumoral-infiltrating lymphocytes