To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in surgical patients with SARS-CoV-2. We found that patient rather than operation factors were the best predictors and used these to create the COVIDsurg Mortality Score (https://covidsurgrisk.app). Our data demonstrates that it is safe to restart a wide range of surgical services for selected patients.

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Background: Abdominal wall hernia is a common surgical condition. Patients may present in an emergency with bowel obstruction, incarceration or strangulation. Small bowel obstruction (SBO) is a serious surgical condition associated with significant morbidity. The aim of this study was to describe current management and outcomes of patients with obstructed hernia in the UK as identified in the National Audit of Small Bowel Obstruction (NASBO). Methods: NASBO collated data on adults treated for SBO at 131 UK hospitals between January and March 2017. Those with obstruction due to abdominal wall hernia were included in this study. Demographics, co-morbidity, imaging, operative treatment, and in-hospital outcomes were recorded. Modelling for factors associated with mortality and complications was undertaken using Cox proportional hazards and multivariable regression modelling. Results: NASBO included 2341 patients, of whom 415 (17⋅7 per cent) had SBO due to hernia. Surgery was performed in 312 (75⋅2 per cent) of the 415 patients; small bowel resection was required in 198 (63⋅5 per cent) of these operations. Non-operative management was reported in 35 (54 per cent) of 65 patients with a parastomal hernia and in 34 (32⋅1 per cent) of 106 patients with an incisional hernia. The in-hospital mortality rate was 9⋅4 per cent (39 of 415), and was highest in patients with a groin hernia (11⋅1 per cent, 17 of 153). Complications were common, including lower respiratory tract infection in 16⋅3 per cent of patients with a groin hernia. Increased age was associated with an increased risk of death (hazard ratio 1⋅05, 95 per cent c.i. 1⋅01 to 1⋅10; P = 0⋅009) and complications (odds ratio 1⋅05, 95 per cent c.i. 1⋅02 to 1⋅09; P = 0⋅001). Conclusion: NASBO has highlighted poor outcomes for patients with SBO due to hernia, highlighting the need for quality improvement initiatives in this group. *Members of the National Audit of Small Bowel Obstruction (NASBO) Steering Group and NASBO Collaborators are co-authors of this study and are listed in Appendix S1 (supporting information) Funding information

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BACKGROUND:The surgical removal of impacted third molars is one of the most frequently performed procedures in oral surgery with complications such as postoperative pain, swelling and trismus. Ideal analgesic to be administered after the surgical removal of impacted third molar should alleviate pain and associated symptoms, facilitate healing, and cause no undesirable side effect and for which we usually administer nonsteroidal anti-inflammatory drugs (NSAIDs). In this study comparison of efficacy of nimesulide,diclofenac sodium and ibuprofen to control postoperative sequelae in surgical removal of impacted mandibular third molars has been undertaken. AIM: To compare drug efficacy in terms of edema, pain and trismus and to compare the side effects of the drugs and to suggest a better pharmaceutical agent that resumes to normalcy at earliest. METHODS AND MATERIAL:Total of 30 patients reporting to the Department Of Oral And Maxillofacial Surgery, KLE Institute of Dental Sciences was included in the study. Pre and post-operative pain, trismus, swelling and adverse effect of drugs were recorded. STATISTICAL ANALYSIS USED: p value and t value test (Test of significance of value) were used to compare the results. RESULT: Nimesulide proved to be the analgesic and anti-inflammatory drug of choice for short term therapy as it demonstrates minimal side effects and early rate of recovery from postoperative sequelae of pain, trismus and swelling after surgical removal of mandibular 3rdmolar. But long term use should be considered and more studies should be carried out regarding long term therapy of Nimesulide in terms of safety and efficacy. HOW TO CITE THIS ARTICLE: