Background: Inguinal hernia is a one of common diagnosis which is frequently encountered in routine clinical practice. The Lichtenstein technique (tension free mesh repair) is currently the gold standard in open inguinal hernia repair. Currently chronic groin pain (Inguinodynia) is one of the common complications after hernia repair and it may affect quality of life and it has been reported in 16% to 62% of the patients.Methods: This prospective, randomized study was conducted in the department of general surgery in S.M.S. Medical College and attached group of hospitals, Jaipur from May 2014 to December 2015. All patients of 18-80 years old, who were admitted for elective inguinal hernia repair, were included for the study. Patients with bilateral, recurrent, irreducible or incarcerated hernia, pregnant patients and patients with co morbid conditions, were excluded from the study.Results: Mean age was 46.5 years in absorbable group and 45.4 years in non absorbable group. Male to female ratio was 142:13 in absorbable group and 143:12 in non absorbable group. Post operative pain was measured by VAS score. Mean postoperative pain (VAS score) was lower in absorbable sutures group as compared to non absorbable group at 3 months (0.92±0.879 vs. 1.23±1.2; p=0.013) and at 6 months (0.48±0.57 vs. 0.77±0.65; p≤0.001), which was significant.Conclusions: Patients with absorbable suture for mesh fixation has less groin pain as compared to non-absorbable suture in hernia repair during 6 months follow up period.
Altered calcium homeostasis, including vitamin D deficiency, was found to be associated with subclinical atherosclerosis and low bone mineral density. 6 Vitamin D insufficiency has been linked to cardiovascular diseases, infections, and even cancer in recent large epidemiological studies. 7 Low serum levels of 25-ABSTRACT Background: This study aimed to investigate the relationship between serum vitamin D level and carotid artery intima-media thickness in ischemic stroke patients. The correlation of vitamin D and carotid artery intima media thickness in ischemic stroke patients had conflicting results in different parts of the world. Methods: 217 patients with CVA infarct were selected for analysis between ages 45 and 80 years admitted at our hospital from January 2014 to December 2015. Measurements of serum vitamin D concentration and Carotid-IMT were made by electrochemiluminescence immunoassay and B-mode ultrasound, respectively. Confounding variables like diabetes, hypertension, smoking, alcohol, tobacco, dyslipidemia, BMI, CRP, Serum uric acid, duration of sunlight exposure, prior history of drug intake or fracture and Serum calcium were considered. 200 age and sex matched controls were taken. Questionnaires were used for data collection and multiple linear regression analysis and correlation analysis were used. Results: The mean serum level of vitamin D was 19.14±9.45 SD ng/mL and average IMT was 0.78±0.09 SD mm with pearson coefficient of (-0.36) significant at 0.01 level. The R 2 value was 0.13. Conclusions: Correlation analysis found an inverse relationship between serum vitamin D level and carotid-IMT in ischemic stroke patients.
Purpose -The purpose of this paper is to assess the nutritional status and quality of life in patients according to the clinical severity of liver cirrhosis. Design/methodology/approach -A total of 151 cirrhotics were selected for study. Nutritional assessment was done by anthropometry, subjective global assessment, malnutrition universal screening tool, biochemical estimations and 72-hour dietary recall. Quality of life was assessed by chronic liver disease questionnaire. Findings -Child's status was A/B/C in 29/68/59, respectively. Muscle and fat depletion was significantly higher in grade C patients as compared to grade A and B patients. Incidence of malnutrition was lowest in grade A patients (72.4 percent) and highest in grade C patients (90.74 percent) ( p ¼ 0.00). Calorie and protein intake was significantly lower in grade C patients compared to grade A and B patients ( p ¼ 0.00). Child Pugh score was found to be an independent risk factor for various nutritional and clinical parameters.Research limitations/implications -The data presented reflect the assessment of a very small cohort of these patients and should be done on a larger scale. Practical implications -Looking into the high prevalence of malnutrition and the negative impact of disease severity, nutritional assessment of these patients should be done on a regular basis and nutritional therapy planned accordingly. Originality/value -Data on malnutrition from India are scarce. This study is a small attempt to throw light on the nutritional status and its variation according to clinical severity of liver cirrhosis.
INTRODUCTIONExposure to sunlight and taking food rich in vitamin D can meet our daily requirements.1,2 Low serum levels of 25-hydroxyvitamin D (25(OH)D) is also shown to be associated with insulin resistance. 3,4 Vitamin D insufficiency has been linked to cardiovascular diseases, infections and even cancer in recent large epidemiological studies.5 Rise in serum cholesterol is associated with increase in cardiovascular diseases. 6,7 Studies have also demonstrated that 25-hydroxyvitamin D deficiency is a novel CV risk factor, predicting both CV events and mortality.8 Vitamin-D deficiency is associated with changes in PTH, calcium, phosphorus, and 1,25-dihydroxyvitamin D levels (1,25[OH]2D). 9 METHODSA case control study where all cases of ischemic stroke admitted from neurology clinic , OPD and medicine wards of LLR and associated hospitals, Kanpur, India from January 2014 to December 2015 and age and sex matched controls not having ischemic stroke were taken after informed consent.Age group >30 years irrespective of sex with diagnosis of ischemic stroke by CT scan or MRI brain were included in the study and patients with valvular heart disease, cardiomyopathy, congenital heart disease and connective tissue disorders were excluded. ABSTRACTBackground: This study aimed to investigate the relationship between serum vitamin D level and lipid profile in ischemic stroke patients. Methods: 217 patients with ischemic stroke were selected for analysis between ages 45 and 80 years admitted at our hospital from January 2014 to December 2015. Measurement of serum vitamin-D concentration was made by electrochemiluminescence immunoassay. Confounding variables like diabetes, hypertension, smoking, alcohol, tobacco, BMI, CRP, S. uric acid, duration of sunlight exposure, prior history of drug intake or fracture and S. calcium were considered. 200 age and sex matched controls were taken. The source of data was questionnaires and multiple linear regression analysis and correlation analysis were used. Results: A positive correlation was seen between vitamin D and serum cholesterol, VLDL, LDL, triglycerides, cholesterol/HDL ratio and LDL/HDL ratio but inverse correlation between vitamin D and HDL. Conclusions: In ischemic stroke patients increase in vitamin D is associated with increase in atherogenic lipids.
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