An Oil & Gas company experienced an issue with communication to the Sub surface safety valve (SSSV). To address this issue, a unique solution was developed to avoid the need for a workover and restored surface communication with the SSSV. One of the offshore wells in United Arab Emirates developed a blockage in the Control Line (CL), leading to an inoperational SSSV. As a result, it became necessary to close the well. This situation would normally continue until a completion workover could be scheduled. An alternative solution was implemented in this well and restored production through the SSSV without the need to perform a workover. After collecting data such as wellhead details, SSSV profile, and production history, a custom Safety Valve communication system was designed and installed. The Lower Master Valve was modified to allow an in-tubing control-line communication, which in turn located the retrofit SSSV. The old CL was also isolated as part of this operation. Over two stages of operation, the wellhead modification was performed and the installation of a replacement surface controlled SSSV, wet connect, CL, and CL hanger was completed. The system was then tested successfully prior to handing the well back to production. The installation of this system saved the cost of rig mobilization and completion recovery as a barge was utilized to install this system as opposed to a workover rig with all the associated additional resource and costs. Supported by flow modeling prior to design and installation, the installed system maintains its integrity while the well is producing at normally expected flow rates. This is a retrofit solution that can be engineered to suit any well with various combination of wellheads and downhole completion accessories. The system follows oilfield standards as required for a safety-valve barrier. It can be used to extend the production duration of the mature wells before an expensive workover operation becomes necessary. The type of wellhead penetration used does not affect the functionality of the existing wellhead valves. Installation of this system saved the cost for a workover rig, replacement completion equipment, and brought a previously shut-in well into production. This system provides a significantly safer alternative compared to the restrictive storm-choke devices and ultimately brings the well back online, while adhering to industry standard definitions for surface-controlled SSSVs.

Depression is momentous mood chaos marked by a mixture of symptoms that interfere with a person’s daily activities. The oral administration serves dose dumping issues of therapeutic molecules in specially targeted delivery. So, the external auditory canal pathway was explored to deliver the API and it help to bypass the above-mentioned problem. Sonication bath method was used to prepare bio-nanosuspension loaded with escitalopram and biopolymer extracted from Tagetes patula. Different ratios of drug and biopolymer were considered and 10 formulations were formulated followed by evaluation parameters like SEM, FTIR for biopolymer and ex-vivo, stability, drug release studies, etc., for the final formulation was performed. Formulations were examined through many evaluation parameters, such as content uniformity, pH, in-vitro drug release, and many more. It was found that STP 1 (1:0.5) was the best formulation. From pharmacokinetic data and in-vitro studies revealed and concluded that acoustic meatus is a feasible pathway for molecules delivery to the brain for depression treatment.

In multilayered reservoirs, major focus has been on the usage of smart well completion technologies to help improve recoveries, particularly with technological improvements and an increasing expanse of opportunities in more challenging and rewarding assets. The fundamental focus has been to design well completions that integrate several surface/subsurface sub zones and automate the flow control from each zone. In Multi zone Smart Completion Wells where significant investment is made to complete smart wells with remotely controlled inflow control valves (ICV), reservoir sweep & drain accessibilities becomes decisive when evaluating the efficiency of recovery and long-term field development strategy. Smart completion designs for multi-lateral wells present many challenges in terms of completion deployment and interventions in life of well. The complexity of operations increases with deviation, type of completion equipment, number of zones and planned interventions. In offshore, UAE a similar multilateral well was designed to be completed with 4 zone smart completion and had a mandatory requirement of accessibility to lower most drain (for future interventions) with the ability to plug the lower drain till future requirements arises. A solution is to utilize nipple & blanking plug in lower most drain, which was implemented in this well. Upon successful deployment of completion, plug was retrieved on coil tubing and lower drain accessibility was confirmed. However, during re-installation of blanking plug on coil tubing in deviated section, issues were encountered to pass through the ICV profiles. In attempts to pass through ICV profiles, blanking plug and running tool got disconnected from coil tubing, leaving the fish inside one of ICV valve. Several attempts were made to retrieve the blanking plug with rig on coil tubing without success by using thru-tubing fishing equipment options available in country. Well was suspend to work-out fishing strategy & evaluate availability of fishing equipment worldwide. Consideration was done for design and manufacture application specific fishing tools to perform workover with barge for such smart completion, as it includes a number of downhole components that makes its retrieval more challenging, and there are no standard procedure or provision in place to retrieve such complex completions in highly deviated section. A barge was mobilized with coil tubing, which performed the fishing operation as planned. Careful selection of equipment's, BHA and operational parameters resulted in successful retrieval of blanking plug & running tools. Accessibility to well was gain and confirmed. This paper presents the situation that was faced, the remedial work done to complete well, fishing operations and the subsequent factors considered for choice of equipment and operation on well. This paper concludes a detailed account of factors to consider for planning smart completions in horizontal multilateral wells & the successful fishing operation – an excellent example of how careful planning, dedicated project management, specialized design fishing tools, experienced personnel and a collaborative relationship between team's leads to a successful operation and prevented an extremely expensive workover of a high technology completion well.