Objectives. Ameloblastoma is a slow-growing epithelial odontogenic neoplasm of the jaws with a high recurrence rate. The main treatment strategies for this lesion are radical or conservative surgical approaches. The aim of the present study was to analyze clinical presentations, histological types, and treatment strategies of recurrent ameloblastoma and to define its disease-free survival (DFS) rate. Materials and Methods. Twenty-four cases of recurrent ameloblastomas, treated between January 2009 and July 2021, were enrolled in this study. Medical files from each patient, including gender, age, size of the lesion, localization, patient complaints, clinical manifestation, radiographic appearance, histological type, surgical management, and treatment results were reviewed and analyzed retrospectively. Result. Out of 69 operated primary ameloblastomas, the rate of recurrence was 35%. Out of 24 recurrent cases, 21 developed after conservative treatment and 3 after radical treatment. In most cases, recurrences were found in the mandible (n = 20). A unilocular pattern was predominant in radiographic examination (44%). Estimated 3-year DFS was 84.5 ± 4.8%, and the 5-year and 10-year DFS were 73.0 ± 6.3% and 43.9 ± 8.343.9 ± 8.3%, respectively. Conclusion. Results obtained in the present retrospective study proved the necessity of long-term follow-up after both conservative and radical treatment approaches. The DFS median in our study was 8 years (95% CI 6 years–10 years). For recurrent cases, radical resection with histologically free margins after exact MRI determination of the ameloblastoma border within the soft tissues should be considered as the method of choice to avoid secondary recurrence.
The main purpose of the study is to build 3D model of temporomandibular joint and mandible using programs for modelling and design, research stress and strain in cartilage and bone of model depending on different contraction of chewing muscles (especially lateral pterygoid muscle). There were used such methods as computer tomography data, finite element method and analysis topography of lateral pterygoid muscle on cadavers. In results of study was obtained maximal stress in anterior and distal parts of articular disc between 1,4–3 MPa and 0,4–1 MPa. Thus, static loads of articular disc were different, depends on force of contraction lateral pterygoid muscle. Muscle disturbances (hyperfunctioning, atrophy etc.) should be considered in treatment of temporomandibular dysfunction and examined on magnetic resonance investigation if it is present in the same patient.
The aim: To propose the algorithm of complex rehabilitation of patients with iatrogenic occlusal disorders combined with vertical malocclusion and prove its efficiency. Materials and methods: 55 patients with iatrogenic occlusal disorders combined with vertical malocclusion aged from 23 to 47 years old (mean age 36.1±5.2 years) including 32 females and 23 males were examined at Dental Medical Center of Bogomolets National Medical University during 2019-2021 years. All patients before and 6 months after treatment underwent clinical and laboratory examination, X-ray, electromyography, T-Scan Digital Occlusal Analysis. Results: In all 3 groups of patients we observed complete disappearance or significant reduction of complaints and symptomatic manifestations after 6 months of complex rehabilitation. Conclusions: Our study showed that the proposed algorithm of complex rehabilitation of patients with iatrogenic occlusal disorders combined with vertical malocclusion, which provides a multidisciplinary and individualized approach, improves the efficiency of orthodontic treatment of such patients and significantly reduces the duration of treatment in all 3 groups. This sequence of diagnostic and treatment measures gives the best opportunities for the patient to achieve maximum functional and aesthetic result.
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