Introduction: Epilepsy is a chronic disease and affects up to 80 million people worldwide. About two-thirds of these patients are in middle and low-income. Refractory epilepsy can occur in 20 to 30% of patients. Structural brain lesions are the principal cause of refractory epilepsy. In particular, brain tumors are the second etiology that requires surgery in specialized epilepsy centers. Furthermore, low-grade tumors have a higher epileptogenic potential compared to those of high-grade tumors associated with epilepsy. The dysembryoplastic neuroepithelial tumor (DNT) and ganglioglioma correspond to the foremost found in clinical cohorts. Objective: Evaluate the surgical outcome in patients undergoing epilepsy surgery by brain tumors. Materials and methods: A sample of 86 patients undergoing epilepsy surgery were selected, between 0 and 60 years old, who underwent preoperative evaluation with Video-EEG, and the histopathologic result was tumor. Results: 38 patients were aged from 19 years old; 48 patients were aged below 19 years old. The most prevalent histological type was DNT with 37.2% followed by ganglioglioma with 22.1%. The main site of involvement was the temporal lobe, accounting for 66.3% of all series. The rate of patients classified as Engel I was 77.9% in the first year and 74% in the fifth year of follow-up. Normal EEG-based activity, Semiologic concordance and ictal EEG concordance were associated with the best result. The use of invasive EEG did not alter the prognosis. In the multivariate analysis between the variable ictal EEG, Interictal EEG, semiology and backgroud activity, the last normal was associated with favorable outcome (p = 0.012). Isolated lesionectomy was associated with worse results in seizure control. Conclusion: The electroencephalographic data present an important predictive value in the presurgical evaluation. A broader surgery (enlarged lesionectomy) or lobectomy was associated with better outcome, as well as the presence of temporal surgery presented a better outcome in relationship to non-temporal surgeries.
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