In this paper, we provide a retrospective cohort study with patients that have been hospitalized for general or intensive care unit admission due to COVID-19, between March 3 and July 29, 2020, in the state of Bahia, Brazil. We aim to correlate those patients’ demographics, symptoms and comorbidities, with the risk of mortality from COVID-19, length of hospital stay, and time from diagnosis to definitive outcome. On the basis of a dataset provided by the Health Secretary of the State of Bahia, we selected 3,896 hospitalized patients from a total of 154,868 COVID-19 patients that included non-hospitalized patients and patients with invalid registration in the dataset. Then, we statistically analyzed whether there was a significant correlation between the patient record data and the COVID-19 pandemic, and our main findings reinforced by the use of a multivariable logistic regression were that older age (Odds Ratio [OR] = 1.03, 95% Confidence Interval [CI] = 1.03-1.04, p-value (p) <0.001), an initial symptom of shortness of breath (OR = 1.88, 95% CI = 1.60-2.20, p < 0.001), and the presence of comorbidities, mainly chronic kidney disease (OR = 2.41, 95% CI = 1.67-3.48, p < 0.001) are related to an increased risk of mortality from COVID-19. On the other hand, sore throat (OR = 0.74, 95% CI = 0.58-0.95, p = 0.02) and length of hospital stay (OR = 0.96, 95% CI = 0.58-0.95, p < 0.001) are more related to a reduced risk of mortality from COVID-19. Moreover, a multivariable linear regression conducted with statistically significant variables (p < 0.05) showed that age (OR = 0.97, 95% CI = 0.95-0.98, p < 0.001) and time from diagnosis to definitive outcome (OR = 1.67, 95% CI = 1.64-1.71, p < 0.001) are associated with the length of hospital stay.
Coeficiente de Pearson: correlação entre as variáveis notificação de casos de dengue e fatores climáticos Pearson's coefficient: correlation between variables notification of dengue cases and climate factors
Este artigo tem por objetivo analisar a rede de coautoria formada a partir do número de publicações e interações entre os autores do Programa de Pós-Graduação Multi-institucional em Difusão do Conhecimento – (PPGDC) para verificar se a partir da entrada de novos docentes e discentes houve um aumento no número de produções acadêmicas e de coautorias no período de 2017-2019. A metodologia utilizada se caracteriza por uma abordagem exploratória, cujos métodos adotados são a análise de redes sociais e a revisão de literatura que investigou estudos sobre o conceito de ARS de coautoria e produção científica, utilizando os motores de busca: Science Direct e Google Scholar. A coleta dos dados ocorreu através da Plataforma Sucupira da CAPES. Os relatórios foram disponibilizados em formato “.xls”, com o uso do software Microsoft Excel, e a partir das análises, tornou-se possível a criação e composição da rede de produção intelectual e coautoria do PPGDC, através das ferramentas Pajek e Gephi. Como resultado principal, foi possível observar que, em virtude da introdução de novos participantes ao Programa, houve um acréscimo do número de autores e relações entre os mesmos. Apesar disso, nota-se que a rede é constituída por grandes grupos conectados, que publicam intensamente entre seus pares, mas com pouca conexão entre esses grupos, evidenciando a necessidade de uma maior cooperação e colaboração científica.
Systemic Arterial Hypertension (SAH) can generate complications such as stroke, myocardial infarction, kidney disease, arteriosclerosis, loss of vision, erectile dysfunction and cognitive dysfunction. Among people who know they suffer from hypertension, 50% use medication and of those only 45% have their blood pressure kept under control. SAH is a multifactorial clinical condition characterized by elevated and sustained blood pressure levels (BP, where systolic BP ≥ 140 mmHg and diastolic BP ≥ 90 mmHg). Faced with sparse investigative studies on the causes of SAH in individuals, the dictates of the pharmaceutical industry and the use of in vitro or inconclusive clinical studies, this paper presents the state of the art about the treatment of SAH based on a multifaceted view, including aspects about the physiology of SAH, food and PANC as alternatives for the prevention and control of SAH, as well as an approach on the importance of scientific rigor in the manufacture of medicines.
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