A B S T R A C TBackground: The experience of previous sizable outbreaks may affect travelers' decisions to travel to an area with an ongoing outbreak. Methods: We estimated changes in monthly numbers of visitors to the Republic of Korea (ROK) in 2015 compared to projected values by selected areas. We tested whether areas' experience of a previous SARS outbreak of ≥100 cases or distance to the ROK had a significant effect on travel to the ROK during the MERS outbreak using t-tests and regression models. Results: The percentage changes in visitors from areas with a previous SARS outbreak of ≥100 cases decreased more than the percentage changes in visitors from their counterparts in June (52.4% vs. 23.3%) and July (60.0% vs. 31.4%) during the 2015 MERS outbreak. The percentage changes in visitors from the close and intermediate categories decreased more than the far category. The results from regression models and sensitivity analyses demonstrated that areas with ≥100 SARS cases and closer proximity to the ROK had significantly larger percentage decreases in traveler volumes during the outbreak. Conclusions: During the 2015 MERS outbreak, areas with a previous sizable SARS outbreak and areas near the ROK showed greater decreases in percentage changes in visitors to the ROK. MethodsWe used monthly international traveler statistics from TOURGO, the Korea tourism knowledge and information system, maintained by the Korea Culture and Tourism Institute [7]. The data include numbers of inbound non-citizen short-term visitor arrivals by area following the international guideline from the United Nations World Tourism

Abstract. Eighty patients with Parkinson's disease participating in a drug trial of L‐dopa were studied prospectively for the development of antierythrocyte, antinuclear, and antiglobulin activities. The median age of the group was 65 years; and the median dose of L‐dopa was 4 g/day. Five of the 80 patients developed positive red cell antiglobulin tests after 8 to 11 months of therapy. Three of these had IgG only on their red cells; eluates prepared from these cells reacted strongly with all except Rhnull erythrocytes, suggesting Rh specificity. Complement only was detected on the cells of the other 2 patients. One of the 5 individuals with positive erythrocyte antiglobulin tests became anemic. Significant titers of antinuclear antibody appeared in 9 patients and significant increases in titers of serum antiglobulins were found in 9 patients, 2 of whom also had a positive ANA test. These results indicate that administration of L‐dopa is associated with induction of a variety of autoantibodies. The mechanism responsible for this phenomenon is unknown.

Patient: Male, 58Final Diagnosis: Axillary • chest and abdominal wall hematomaSymptoms: Discolored/bruised chest and abdominal wallMedication: —Clinical Procedure: Coronary angiogram via trans radial routeSpecialty: CardiologyObjective:Diagnostic/therapeutic accidentsBackground:Radial artery access during coronary angiography has gained popularity as there are fewer associated complications when compared with femoral artery access. However sporadic complications can occur following radial artery catheterization. A rare case of axillary, chest wall and abdominal hematoma is presented following radial artery catheterization.Case Report:A 58-year-old man with hypertension, type 2 diabetes, with a history of smoking, underwent elective coronary artery angiography via the right radial artery route. He was discharged from care without event, before returning 24 hours later with a large hematoma of the right axilla, extending to the anterior chest wall and abdomen. One year previously, he underwent coronary artery angiography with catheterization of the femoral artery, which was without complications. On this occasion, after resolution of the hematoma, he underwent coronary artery bypass graft (CABG) surgery.Conclusions:This case has reported a rare complication of radial artery catheterization that involved extensive hematoma involving the chest, abdominal wall, and axilla. Although such complications may be rare, a high level of vigilance should be maintained for rare complications in patients undergoing radial artery catheterization.