It. %MbIMW~dbdSb AFAMRL-TR-85-036(0 DIAZEPAM AND ITS EFFECTS ON PSYCHOPHYSIOLOGICAL W4EASURES OF PERFORMANCE (U)Anthony NOTICESWhen US Government drawings, specifications, or other data are used for any purpose other than a definitely related Government procurement operation, the Government thereby incurs no responsibility nor any obligation whatsoever, and the fact that the Government may have formulated, furnished, or in any way supplied the said drawings, specifications, or other data, is not to be regarded by implication or otherwise, as in any manner licensing the holder or any other person or corporation, or conveying any rights or permission to manufacture, use, or sell any patented invention that may in any way be related thereto. TECHNICAL REVIEW AND APPIOVAL AFAMRL-TR-85-036This report has been reviewed by the Office of Public Affairs (PA) and is releasable to the National Technical Information Service (NTIS). At NTIS, it will be available to the general public, including foreign nations.The voluntary informed consent of the subjects used in this research was obtained as required by Air Force Regulation 169-3.This technical report has been reviewed and is approved for publication. FOR THE COMIMANDER TITLE Iclude Security Clasification)62202F 7184 14 07See reverse side. PERSONAL AUTHOR(S)Capt Anthony P. Rizzuto*, Dr. This study used a 5 mg oral dose of diazepam (valium) and placebo to test potential performance degradation under the influence of a minor tranquilizer. Dependent variables included a wide range of visual and auditory evoked response measures, as well as behavioral, memory, and physiological tasks that generated the measurement of 57 separate indices of human performance for each of 24 subjects during each of four measurement sessions. These dependent variables have been chosen as standardized tasks to be included in a neurophysiological test battery currently under development and testing by the Air Force Aerospace Medical Research Laboratory. This report describes the rationale for usin. these measures as indices of drug effects and outlines recent research using diazepam to induce performance decrements. Results of the experiment showed no generalized substantive effect at this dosage level on the performance variables studied. A multivariate analysis of variance for repeated measures, a contrast statistic, and a power analysis DISTRIBUTION/AVAILABILITY OF ABSTRACT 21. ABSTRACT SECURITY CLASSIFICATIONUNCLASSIFIEO/UNLfMITEO 1 SAME AS RPT '-DTIC USERS 0