Introduction: 3
Plasma cell granuloma mainly occurs in lungs but can occur in any other organ or soft tissue . It occurs very rarely in oral cavity. We
have also reviewed different articles describing plasma cell granuloma in oral cavity. We search the articles in google scholar and pubmed with
keywords plasma cell granuloma in oral cavity, buccal mucosa, gingiva, tongue. A Case report: 39 year old male came with a chief complaint of
growth on left buccal mucosa. HPE discovered parakeratinized stratied squamous epithelium, showing focal ulceration and underlying dense
connective tissue stroma. On the basis of clinicopathological ndings the diagnosis of plasma cell granuloma was made. Discussion: Plasma cell
granuloma is a benign lesion but its exact aetiology, behaviour and prognosis is not completely known. We can give emphasis on frozen
histopathology intraoperatively to avoid unnecessarily extensive and potentially destructive surgery as the treatment plan.
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