Introduction: Foreign body-associated sialadenitis of submandibular gland is not often and scarce within the literature. In this study, a report of a piece of Nail-like fish bone foreign body entering the Wharton’s duct causing an acute sialadenitis is presented. Foreign bodies must be explored and all suspected areas must be examined carefully for avoiding secondary problems and surgeries in the future. Foreign bodies in the oral and maxillofacial region are often experienced after trauma and dental treatment. Case Report : We describe a case of obstructive sialadenitis in the submandibular gland caused by penetration of a fish bone in a 68-year-old man. He had swelling and spontaneous pain in the left submandibular region. The radiographic examination didn't show foreign body in the submandibular gland. Initially, we diagnosed obstructive sialadenitis in the left submandibular gland and the study suspect that salivary stone might be the cause of this swelling so compressing and milking of Wharton duct. The foreign body measured 1.3 cm *3 mm*2 mm and was a nail-like object. On pathological examination, the foreign body was found to be a fish bone (cartilage-like organic material). Conclusion: This case demonstrated that precise and proper inspection and examination, milking and then paying attention to the secretion of salivary gland lead to proper diagnosis and after that suitable treatment, so this could reduce costly assessment and treatment, also lessen bewilderment of the patient.

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Background and Aim: Sialoliths are the most common salivary gland disease, Among them, there are rare sialoliths that have a size of more than 15 mm in one dimension, and salivary stones larger than 30 mm in one dimension is megalith that are very rare. Depending on the location and size of the stone, there are different diagnostic and therapeutic methods. In this article, we review the articles about salivary megaliths of unusual and gigantic size, the cause of stones formation and the method of diagnosis and treatment of salivary megaliths. In this review article finding the number of reported salivary megaliths, causes, mechanism of stone formation, clinical presentation, diagnostic and therapeutic methods were written. Materials and Methods: In this article review, Information was extracted through searches in databases by entering the keywords. Articles with incomplete data or articles that were less relevant to the topic or reported articles with giant stones smaller than 30 mm were excluded. Results: A total of 77 articles, 85 patients suffering from megaliths and 86 salivary megaliths with a size of 30 mm and upwards have been reported up to now. The largest size is reported to be 83 mm. Megalith is more common in men and in the submandibular duct. Conclusion: salivary megaliths are rare and Depend on the location of megaliths various diagnosis and treatment are available. The exact cause of the formation of them is unknown and further research is needed to identify the etiopathogenesis of the formation of these kind of gigantic salivary stones.