The natural aging process brings about some inevitable consequences, such as olfactory dysfunction, which is also frequently linked to numerous neurodegenerative disorders. Many age-related dementia, such as Alzheimer's disease, Vascular dementia, Parkinson's disease, and Frontotemporal Dementia often display olfactory dysfunction. Despite the overwhelming evidence of above mentioned facts, the symptomatic relevance and potential clinical and pre-clinical value of olfactory dysfunction remains overlooked by many clinicians and public alike. Olfactory dysfunction has strong practical implications on daily activities and, although not as prominent as in other mammals, olfaction is still an evolutionarily relevant sense involved in human survival (e.g., smelling gas; bad food). In this work, we provide a brief review of current research related to the olfactory dysfunction profiles in different types of dementia. Additionally, we present a compilation of accessible, easy to use olfaction assessment tools; and highlight future directions in terms of improving clinical diagnosis in patient care and research.

In recent years, health promotion has been introduced as a promising strategy for the public health field. The current study is intended to link nutrition into the recent debate on health promotion, analyzing the role of nutritionists in this process. Given the complexity of the Brazilian nutritional situation due to the nutritional transition currently under way in the country, the health promotion proposal points to both new perspectives and challenges for eating and nutrition. New demands in academic training and the nutritional care model tend to foster a search for partnerships, innovation in eating practices, and nutritional education aimed at the achievement of nutritional citizenship.

We performed a multilevel meta-analytic review, complemented with both sensitivity analysis and robust variance estimation (RVE) method, to systematically assess the effects of working memory training on healthy older adults.  We found small significant gains on verbal and visuospatial working memory, however the effects were maintained at follow-up only for verbal working memory.  Far-transfer effects were not verified, except for the studies whose Cattell Test was used to assess reasoning.  The effects of working memory training were moderated by the adopted measures, type of training, training length and duration, and baseline performance.  Moderator analysis did not show the influence of type of control group (active versus passive), except for one comparison: visuospatial WM at posttest.

Several studies have shown that cognitive intervention may be beneficial for people with Alzheimer disease (AD), but literature reviews conducted so far, have yielded mixed and inconclusive results. In this work, through an extensive bibliographic search, we aim: (1) to analyze the efficacy of cognitive intervention in patients diagnosed with AD; (2) to provide an estimate of the feasibility of cognitive intervention; and (3) to review available cost-effectiveness data of this approach. Four randomized controlled trials of cognitive intervention, for patients diagnosed with AD that incorporated cognitive intervention and mock intervention control conditions, were included in the analysis. Only the domain of global cognitive functioning, as measured by Mini-Mental State Examination, showed significant intervention effects. No effects were observed in the remaining domains. Concerning feasibility, high rates of completion and adherence were found. A single randomized controlled trial, with unspecified dementia, suggested cognitive intervention to be cost-effective. Given the currently available dearth of well-controlled and focused trials in AD, these results should be carefully interpreted and remain to be confirmed in the future. There is a clear need for more high-quality research.