The blood pressure and pulse rate of 90 normal rabbits have been studied for various periods of time, from 1 day (accidental death interrupting the observation) to 15 months. The main data are presented in a table containing the blood pressure and pulse rate on the 1st day of observation, the maximum and minimum of both during the entire period of observation of each animal, together with the sex and weight of the animal. Separate tables are given showing the distribution of blood pressure, pulse rate and the "maximum" blood pressure by animals. Detailed data on two animals observed for the longest time are given in tabular form. The anatomical changes that occur in some carotids enclosed in a loop are described and discussed. Considerations on "excitement" and pathological conditions which arise spontaneously in rabbits are given. A criterion for a pathologically high blood pressure in rabbits is proposed. The blood pressure of the normal rabbit ranges between 70 and 170 mm. Hg. The pulse rate, taken simultaneously with the blood pressure, fluctuates between 112 and 300 per minute.

Objetivo. Indagar acerca de la literatura científica emergente a nivel internacional sobre la repercusión de la pandemia por COVID-19 en las adicciones. Metodología. La base de datos Web of Science se utilizó para analizar la literatura científica sobre la pandemia por COVID-19 y la influencia que ésta pueda tener en el ámbito de las adicciones. Resultados. Se identificaron 320 documentos, de los cuales 38 cumplieron los criterios de inclusión. Sobresalieron tres problemáticas: el consumo de tabaco, opioides y alcohol. Según la literatura incipiente, entre los consumidores de opiáceos existe el riesgo de aumento de las sobredosis, así como un empeoramiento del binomio estrés-alcohol y un peor pronóstico de la enfermedad COVID-19 para los fumadores de tabaco. Destaca la preocupación por la disminución de servicios sanitarios focalizados en las adicciones y la salud mental. Conclusiones. La literatura es muy reciente y es necesaria más evidencia científica que arroje luz. Se pone de manifiesto la preocupación por el alcohol, opioides y tabaco, pero se constata la escasez de referencias a adicciones sin sustancia (nuevas tecnologías, juego online) o a los hipnóticos y las benzodiacepinas.

In a prospective study, 140 patients had an oxytocin challenge test with either a continuous or a pulsed infusion (one minute of infusion in every five minutes). Both infusion regimens had similar success rates in terms of uterine contractions (97.1 vs 98.6%). The potency ratio (pulsed versus continuous infusion) was significant at 2.7 (1.27 to 5.2), which means that more uterine activity was induced with each mU of oxytocin with pulsatile than with continuous administration. The total amount of oxytocin required to obtain three good contractions in 10 minutes was about 40% less with pulsed administration than with continuous infusion, but the test took 40 minutes longer with the pulsed than with the continuous infusion (P < 0.01).

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