Mudskippers are amphibious species inhabiting semi-terrestrial ecosystems like mudflats, mangroves, marshy swamps, intertidal regions, and estuaries.  Around 34 diversified species are found across the globe.  Mudskipper belongs to the Oxudercidae family and the subfamily is Oxudercinae.  The occurrence of species is vastly found across the Indo-West Pacific region, the tropical western coast of Africa and in the Indian Ocean.  Mudskippers are known for being the biological indicator and also an indicator of estuarine safety monitoring.  They are used by people for prey-catching baits.  This review paper explains the ecological indicators, taxonomy, species diversity, habitat, behavioural pattern, respiration & kinematics, feeding ecology, reproduction, nutrition content & its medicinal value, and threats to mudskippers.