Taken together these results suggest that the low MIC of A. paniculata methanolic leaves extract (0.06 mg/mL) reduce HO toxicity and more importantly, was in itself effectively inhibitory against S. aureus. Further, our observations suggest that a probable mode of its inhibitory mechanism against S. aureus is by reducing total SOD activity through downregulation of sodA and sodM expressions.

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The cognitive assessment of young motorcyclists under high-noise exposure has not been investigated previously. Therefore, this study aimed to determine the effects of noise-induced cognitive function and reaction time among undergraduate motorcyclists (aged: 19-25). The study design consisted of experimental (ExG; n=30) and controlled group (CoG; n=30). The ExG performed neuropsychological battery test under motorcycle noise (85-90 dBA) and CoG under controlled laboratory noise (<65 dBA). The result revealed that the CoG had significantly better cognitive performance (p < 0.05) and reaction-time as compared to ExG. The results demonstrated the significant effect of motorcycle noise on decreased cognitive performance and increased reaction time.

Saliva cortisol response was investigated from the motorcycling exposure for approximately 50 minutes between low and high noisesensitive (Weinstein Noise Sensitivity Scale) young riders (19-25 years). The results showed significant difference (p < 0.05) in salivary cortisol concentrations in High-Noise Sensitive group (n = 27). Significant gender differences were found (p < 0.05) among the Low-Noise sensitive group (n = 30), after ride. Cross-analysis between groups was significant (p < 0.05) for before ride cortisol levels of Low-Noise sensitive group. This study suggests that subjective noise sensitivity plays a vital role in increased cortisol level among noise sensitive riders.